HYPERCHOLESTEROLEMIA

This study tests whether sharing genetic test results with veterans can help them feel more confident about taking statins to lower cholesterol and prevent heart disease. About 410 veterans aged 40–75 with diabetes or heart disease who are not currently on statins will receive th…

This study compares two food supplements, Cynacol and Metacol, to see which is better at lowering LDL (bad) cholesterol in people with mild high cholesterol. Researchers will track cholesterol levels and side effects over 90 days in 40 adults aged 35-70. The goal is to find a saf…

This study tests whether a church-based program led by community health workers can help Black adults in New Orleans lower their risk of heart disease, high blood pressure, diabetes, and high cholesterol. About 806 adults aged 40 and older with at least three heart disease risk f…

This study will follow 3,000 Italian adults who are already taking inclisiran, a medication for high cholesterol. Researchers want to see how consistently patients take the drug and how much it lowers their LDL (bad) cholesterol in everyday practice. The goal is to understand rea…

This early-stage study tests a single dose of VERVE-201, a gene-editing treatment, in 36 adults with high cholesterol and triglycerides that don't respond to standard therapies. The treatment aims to turn off a liver gene (ANGPTL3) to lower fat levels in the blood. The main goal …

This trial tests whether corn or avocado oil, as part of a controlled diet, can improve cholesterol levels in adults with mildly to moderately high non-HDL cholesterol. Participants follow two 21-day diet periods with each oil, separated by a 21-day break. The study involves 54 m…

This study tests whether starting cholesterol-lowering treatment in the emergency department can help prevent future heart attacks and strokes. It involves 130 adults aged 40-75 who are at risk for heart disease but not yet on preventive medication. The approach follows national …

This study looks at how consistently Italian patients take their PCSK9 inhibitor injections for high cholesterol and how well the treatment works in everyday life. Researchers will track 5,000 adults aged 18-80 who are already prescribed these drugs, measuring adherence, treatmen…

This study looks at people with lipid disorders—conditions where fats like cholesterol are too high or too low in the blood. Researchers want to learn how these fats cause diseases like hardening of the arteries. Up to 2,000 adults and children (ages 2 and up) will have medical t…

This study looks at how consistently Italian patients take bempedoic acid for high cholesterol and how well it works in everyday life. Researchers will track 1,500 adults aged 18-80 who are already prescribed the drug, measuring adherence, persistence, and LDL cholesterol changes…