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Genetic test aims to get vets on statins and cut heart risk

NCT ID NCT06568601

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study tests whether genetic testing can help veterans at high risk for heart disease start and stick with statin medications. About 410 veterans aged 40-75 with diabetes or heart disease who are not currently taking statins will receive either a genetic report on their statin response and heart risk, or a standard risk report. The goal is to see if personalized genetic information improves cholesterol levels over 15 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Durham VA Medical Center, Durham, NC

    NOT_YET_RECRUITING

    Durham, North Carolina, 27705-3875, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Richard L. Roudebush VA Medical Center, Indianapolis, IN

    RECRUITING

    Indianapolis, Indiana, 46202-2884, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pharmacogenetic and polygenic risk testing

What this could lead to

If successful, this approach could help more veterans lower their cholesterol and reduce heart disease risk by personalizing statin therapy.

What could go wrong

This is a relatively small, early-stage study (410 participants) and focuses on behavior change, not a new drug. Results may not apply to non-veterans or those already on statins.

Conditions

The condition(s) this trial relates to.

atherosclerosis cardiovascular disorder diabetes mellitus Genetic Risk Score Hypercholesterolemia hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.