HYPERCHOLESTEROLEMIA

This study looks at whether having a cancer survivor's regular doctor work closely with their cancer team can better manage heart-related conditions like high blood pressure, diabetes, and high cholesterol. About 800 adults with certain cancers (like breast, prostate, or lung) an…

This study follows 116 people who received an experimental gene-editing therapy for heart disease or high cholesterol. Researchers will monitor them for 15 years to see if any side effects appear and how their cholesterol levels change over time. The goal is to understand the lon…

This study tests different approaches to help patients with high cholesterol and heart disease get the right medicines to lower their cholesterol. About 300 adults at high risk or with established artery disease will take part. The goal is to see which method helps more patients …

This study is for adults with high cholesterol who have already completed an earlier study of the experimental drug MK-0616 (enlicitide decanoate). The main goal is to check the drug's safety over a longer period by tracking side effects. About 3,000 participants will take the dr…

This study tests whether a time-saving, joint-friendly training method called whole-body electromyostimulation (WB-EMS) can lower resting blood pressure and improve other heart-related risk factors in people with mild hypertension who are overweight. About 28 participants will un…

This study tests a drug called inclisiran in about 345 Asian patients with high cholesterol and heart disease or high risk for it. The drug is given as an injection alongside standard statin therapy. The main goal is to see if it safely lowers 'bad' LDL cholesterol more than a pl…

This study tested a combination of two cholesterol-lowering medicines (Pitavastatin and Ezetimibe) in 88 adults with high cholesterol and high triglycerides. The goal was to see if the combo works better than Pitavastatin alone at reducing LDL (bad) cholesterol over 8 weeks, with…

This study tests whether a 30-minute educational website helps people who stopped taking statins due to muscle symptoms make informed decisions about restarting the medication. About 816 participants will either use the website or receive usual care. The goal is to see if the web…

This study checks how often hospital workers have high levels of lipoprotein(a), a type of fat in the blood that can raise heart disease risk. About 2,800 healthcare workers and their family members will give a blood sample. Researchers will track who later has heart problems, bu…

This study looks at how ketogenic diets impact heart health in adults with epilepsy. Researchers will measure cholesterol, blood pressure, weight, and artery thickness over 12 months. Participants are adults 18 or older already on a keto diet or starting the modified Atkins diet.…

This study observes 5,000 adults with high cholesterol who are taking bempedoic acid (alone or with ezetimibe) as part of their normal medical care. Researchers will track changes in cholesterol levels, heart events, side effects, and quality of life over one year. The goal is to…