HER2-POSITIVE METASTATIC BREAST CANCER
Clinical trials for HER2-POSITIVE METASTATIC BREAST CANCER explained in plain language.
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PET scan could personalize breast cancer treatment after drug failure
Disease control Recruiting nowThis study is for people with advanced HER2-positive breast cancer whose disease has worsened after treatment with trastuzumab deruxtecan (T-DXd). Researchers will use a special PET scan (HER2-PET/CT) to see if the cancer still has HER2 targets. If the scan is positive, participa…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE2 • Sponsor: Jules Bordet Institute • Aim: Disease control
Last updated May 26, 2026 06:03 UTC
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New drug aims to break Cancer's growth signals
Disease control Recruiting nowThis early-phase study tests a new drug called BBO-10203 in about 392 adults with advanced solid tumors (like breast, lung, or colorectal cancer) that have not responded to other treatments. The drug works by blocking a key cancer growth pathway. The main goals are to find the sa…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE1 • Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) • Aim: Disease control
Last updated May 26, 2026 05:51 UTC
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New hope for advanced breast cancer patients with brain metastases: Triple-Drug trial launches
Disease control Recruiting nowThis study tests whether a combination of two oral drugs (tucatinib and capecitabine) plus a chemotherapy given directly into the spinal fluid (intrathecal trastuzumab) can help people with HER2-positive breast cancer that has spread to the lining of the brain and spinal cord. Ab…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New test aims to match breast cancer patients to the right drug
Diagnosis Recruiting nowThis study is testing a new, more precise way to measure HER2 protein levels in people with HER2-low metastatic breast cancer. The goal is to see if this test can better tell who will benefit from a drug called T-DXd. About 200 adults with this type of breast cancer will take par…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Diagnosis
Last updated May 26, 2026 05:43 UTC
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Brain scan study aims to catch hidden metastases early in breast cancer patients
Knowledge-focused Recruiting nowThis study looks at whether giving routine brain scans to people with HER2-positive breast cancer that has spread can help find brain tumors early, before symptoms start. About 69 people will get a brain scan at the start, and if no tumors are found, they will be randomly assigne…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: NA • Sponsor: Royal College of Surgeons, Ireland • Aim: Knowledge-focused
Last updated May 26, 2026 05:57 UTC