HER2-POSITIVE METASTATIC BREAST CANCER
Clinical trials for HER2-POSITIVE METASTATIC BREAST CANCER explained in plain language.
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New drug targets Cancer's fuel line in first human trial
Disease control Recruiting nowThis early-phase study tests a new drug called BBO-10203 in people with advanced solid tumors (breast, colorectal, or lung cancer) that have not responded to standard treatments. The drug works by blocking a key cancer growth signal (PI3Kα:RAS). The main goals are to find a safe …
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE1 • Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) • Aim: Disease control
Last updated May 17, 2026 01:02 UTC
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PET scan could predict best next drug for advanced breast cancer
Disease control Recruiting nowThis study is for people with advanced HER2-positive breast cancer whose disease has worsened after a drug called T-DXd. Researchers will use a special PET scan to see if the cancer still has HER2 on its surface. If the scan is positive, participants get a different drug called T…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE2 • Sponsor: Jules Bordet Institute • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New drug cocktail targets breast cancer that invaded the brain
Disease control Recruiting nowThis study tests whether a combination of two oral drugs (tucatinib and capecitabine) plus a chemotherapy given directly into the spinal fluid (trastuzumab) can help people with HER2-positive breast cancer that has spread to the lining of the brain and spinal cord. About 30 adult…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New test aims to match breast cancer patients with the right drug
Knowledge-focused Recruiting nowThis study is testing a new, more precise way to measure HER2 protein levels in people with metastatic breast cancer. The goal is to see if this test can better predict who will benefit from a targeted drug called T-DXd. Researchers will enroll 200 adults with HER2-low breast can…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Brain scan surveillance trial aims to catch metastases early in HER2+ breast cancer
Knowledge-focused Recruiting nowThis study looks at whether it's possible to routinely scan the brains of people with HER2-positive breast cancer that has spread to other parts of the body. These patients are at high risk for brain metastases, which can cause serious symptoms. The study will compare regular bra…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: NA • Sponsor: Royal College of Surgeons, Ireland • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC