Smartwatch and app join fight against metastatic breast cancer
NCT ID NCT07371585
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests the drug trastuzumab deruxtecan (T-DXd) as a first treatment for people with HER2-positive breast cancer that has spread. About 300 participants will take the drug and use digital tools like a smartwatch and pulse oximeter to catch side effects early. The goal is to see if this approach helps control the cancer and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
trastuzumab deruxtecan (T-DXd)
What this could lead to
If successful, this could confirm T-DXd as an effective first-line treatment for HER2-positive metastatic breast cancer, potentially improving how long patients live without needing other therapies.
What could go wrong
This is a Phase 2, single-arm study without a comparison group, so results may not prove superiority over current standards. Side effects like lung inflammation (ILD) are a known risk with T-DXd.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centro Hospitalario Universitario de Santiago (CHUS)
NOT_YET_RECRUITINGSantiago de Compostela, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Complexo Hospitalario Universitario A Coruna
NOT_YET_RECRUITINGA Coruña, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gustave Roussy
NOT_YET_RECRUITINGVillejuif, 94805, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital 12 Octubre
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clinico Universitario de Valencia
NOT_YET_RECRUITINGValencia, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clínico Universitario de Valladolid
RECRUITINGValladolid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital General Universitario Dr. Balmis
RECRUITINGAlicante, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Regional Universitario de Málaga
RECRUITINGMálaga, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Sant Joan de Reus
RECRUITINGReus, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Son Espases
RECRUITINGPalma de Mallorca, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitari Arnau De Vilanova De Lleida
NOT_YET_RECRUITINGLleida, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitari Vall d'Hebrón
RECRUITINGBarcelona, Barcelona, 08035, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Clínico San Cecilio
RECRUITINGGranada, Spain
Contact Email: •••••@•••••
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Hospital Universitario De Fuenlabrada
NOT_YET_RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Leon
RECRUITINGLeón, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Lozano Blesa
RECRUITINGZaragoza, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Virgen Del Rocío
NOT_YET_RECRUITINGSeville, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario de Badajoz
RECRUITINGBadajoz, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario de Basurto
NOT_YET_RECRUITINGBilbao, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario de Canarias
NOT_YET_RECRUITINGSanta Cruz de Tenerife, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario de Valdecilla
NOT_YET_RECRUITINGSantander, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitaro Ramón y Cajal
NOT_YET_RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Català d'Oncologia (ICO) Girona
NOT_YET_RECRUITINGGirona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Català d'Oncologia (ICO) Hospitalet
NOT_YET_RECRUITINGL'Hospitalet de Llobregat, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Instituto Valenciano de Oncologia (IVO)
NOT_YET_RECRUITINGValencia, Spain
Contact Email: •••••@•••••
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Klinikum der Universitaet Muenchen AöR
NOT_YET_RECRUITINGMünchen, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••