BREAST CANCER STAGE IV

This study tests a personalized approach for people with HER2+ metastatic breast cancer. Doctors use a blood test (ctDNA) and scans to decide when to increase or decrease treatments, combined with local therapies and brain-sparing prevention. The goal is to achieve long-lasting r…

This early-phase study is for people with metastatic HR+ HER2- breast cancer that has spread to the bone. Researchers want to find the best dose of the drug abemaciclib when given together with radiation and hormone therapy. The goal is to control the disease and manage side effe…

This study tests a drug called datopotamab-deruxtecan in 20 people with triple-negative breast cancer that has spread to the brain. The goal is to see if the drug can shrink brain tumors. Participants must have new or growing brain metastases and have not had certain prior treatm…

This study tests whether a combination of three drugs (camrelizumab, apatinib, and eribulin) works better than standard chemotherapy for people with advanced triple-negative breast cancer. The trial involves 246 women aged 18 to 70 whose cancer has spread. The goal is to see if t…

This early-phase study tests a new treatment for people with metastatic pancreatic or breast cancer that has stopped responding to standard therapies. The treatment combines two chemotherapy drugs with high-dose vitamins and a stem cell transplant to help the body recover. The ma…

This study tests a new drug called FWD1802 in people with a common type of advanced breast cancer (ER+/HER2-). The goal is to find a safe dose and see if it shrinks tumors. About 99 women with cancer that has spread or cannot be removed by surgery will take part.

This study tests a drug called T-DXd as the first treatment for people with HER2-positive breast cancer that has spread. About 300 participants will receive the drug and use digital tools to track side effects, especially lung issues. The goal is to see how long the drug keeps th…

This study is testing a new type of PET scan that looks for a protein called HER2 on breast cancer cells. The goal is to see if this scan can better predict which patients with advanced breast cancer will benefit from a targeted drug called T-DXd. About 70 women with metastatic b…

This study tests whether drinking tart cherry juice can help prevent nerve damage (neuropathy) caused by the chemotherapy drug paclitaxel in people with breast or ovarian cancer. About 86 participants will be randomly assigned to take either a high or low dose of the juice daily …