BREAST CANCER STAGE IV
Clinical trials for BREAST CANCER STAGE IV explained in plain language.
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New hope for stage IV breast cancer: adding surgery or radiation to targeted therapy
Disease control OngoingThis study looks at whether adding surgery or radiation to a standard drug combination (palbociclib plus letrozole) can help people with newly diagnosed stage IV ER+/HER2- breast cancer live longer. About 200 women with cancer that has spread beyond the breast will receive the dr…
Matched conditions: BREAST CANCER STAGE IV
Phase: NA • Sponsor: UNICANCER • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Diet and diabetes drug may boost breast cancer therapy
Disease control OngoingThis study tests whether a very low-carb (ketogenic) diet, a low-carb diet, or the diabetes drug canagliflozin can prevent high blood sugar and possibly make standard cancer therapy more effective. It involves 15 people with advanced, hormone-receptor-positive breast cancer that …
Matched conditions: BREAST CANCER STAGE IV
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Blood test identifies relapse risk; targeted drug shows promise
Disease control ENROLLING_BY_INVITATIONThis study has two parts. First, it screens people with HR+ HER2-low metastatic breast cancer who are on standard CDK4/6 inhibitor therapy to find those with lingering tumor DNA in their blood—a sign of high relapse risk. Then, those high-risk patients receive the drug trastuzuma…
Matched conditions: BREAST CANCER STAGE IV
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New study sheds light on breast cancer in transgender community
Knowledge-focused OngoingThis study gathers information from multiple hospitals about breast cancer in transgender and gender-diverse adults. Researchers want to understand how the cancer is found, what risk factors are involved, and how it is treated. The goal is to find ways to improve care and reduce …
Matched conditions: BREAST CANCER STAGE IV
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Can a simple exercise test predict heart risks in breast cancer patients?
Knowledge-focused OngoingThis study looks at how well a cardiopulmonary exercise test (CPET) can measure oxygen use in women with HER2-positive breast cancer who have mild heart problems from their cancer treatment. The goal is to see if this test can help predict how their heart and lungs will handle co…
Matched conditions: BREAST CANCER STAGE IV
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC