BREAST CANCER STAGE IV

This study tests whether a very low-carb (ketogenic) diet, a low-carb diet, or the diabetes drug canagliflozin can prevent high blood sugar caused by the cancer drug alpelisib. The goal is to see if controlling blood sugar helps the cancer treatment work better in people with adv…

This study screens people with HR-positive, HER2-low metastatic breast cancer who are taking a CDK4/6 inhibitor. If a blood test still finds cancer DNA after one month, they receive the targeted drug trastuzumab deruxtecan (T-DXd). The goal is to see if T-DXd can delay cancer gro…

This study looks at how well a cardiopulmonary exercise test (CPET) can measure oxygen use in women with HER2-positive breast cancer who have mild heart problems from their cancer treatment. The goal is to see if this test can help predict how their heart and lungs will handle co…

This study gathers information from multiple hospitals about breast cancer in transgender and gender-diverse (TGD) adults. Researchers will look at how the cancer was found, what risk factors were present, what treatments were used, and how well patients did over time. The goal i…