New hope for Hard-to-Treat breast cancer: Real-World study launches
NCT ID NCT07583485
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows about 300 women with HER2-positive breast cancer that has spread. They are getting a three-drug combination (tucatinib, capecitabine, trastuzumab) as part of their normal care. The goal is to see how well the treatment works and how safe it is in everyday medical practice, especially for patients who have already tried other anti-HER2 therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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A.O. "A. Cardarelli"
RECRUITINGNaples, Italy
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A.O.U. "Città della Salute e della Scienza di Torino" - P.O. Sant'Anna
NOT_YET_RECRUITINGTorino, Italy
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A.O.U. "San Giovanni di Dio e Ruggi d'Aragona"
NOT_YET_RECRUITINGSalerno, Italy
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A.O.U. Policlinico "Umberto I"
NOT_YET_RECRUITINGRoma, Italy
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A.O.U.P. "P. Giaccone"
ACTIVE_NOT_RECRUITINGPalermo, Italy
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A.S.L. Napoli 3 SUD - P.O. Apicella
NOT_YET_RECRUITINGPollena Trocchia, Italy
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AORN "Sant'Anna e San Sebastiano" Caserta
RECRUITINGCaserta, Italy
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AORN S.G. Moscati
RECRUITINGAvellino, AV, Italy
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AOU Federico II
ACTIVE_NOT_RECRUITINGNaples, Italy
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AOU delle Marche
ACTIVE_NOT_RECRUITINGAncona, Italy
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ARNAS Civico - Palermo
NOT_YET_RECRUITINGPalermo, Italy
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ASST Papa Giovanni XXIII
RECRUITINGBergamo, Italy
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AUSL della Romagna - IRST-IRCCS "Dino Amadori"
RECRUITINGRimini, Italy
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Azienda Provinciale Servizi Sanitari di Trento - Ospedale Santa Chiara
NOT_YET_RECRUITINGTrento, Italy
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Casa Sollievo della Sofferenza
NOT_YET_RECRUITINGSan Giovanni Rotondo, Italy
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Fondazione Universitaria Policlinico Gemelli IRCCS
NOT_YET_RECRUITINGRoma, Italy
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Humanitas Istituto Clinico Catanese
RECRUITINGMisterbianco, Italy
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I.R.C.C.S. Istituto Clinico Humanitas
NOT_YET_RECRUITINGRozzano, Italy
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IRCCS Centro di Riferimento Oncologico (CRO)
RECRUITINGAviano, Italy
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IRCCS Istituto Tumori "Giovanni Paolo II"
RECRUITINGBari, Italy
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IRCCS Ospedale Policlinico San Martino
ACTIVE_NOT_RECRUITINGGenova, Italy
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IRCCS Ospedale San Raffaele
RECRUITINGMilan, Italy
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Istituto Europeo di Oncologia
RECRUITINGMilan, Italy
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Istituto Nazionale Tumori "Fondazione G. Pascale"
RECRUITINGNaples, Italy
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Istituto Oncologico Veneto I.R.C.C.S.
RECRUITINGPadova, Italy
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La Maddalena
NOT_YET_RECRUITINGPalermo, Italy
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Mons. Dimiccoli P.O. Barletta
NOT_YET_RECRUITINGBarletta, Italy
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Ospedale "Guglielmo Da Saliceto"
RECRUITINGPiacenza, Italy
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Ospedale "Sandro Pertini" - A.S.L. Roma 2
NOT_YET_RECRUITINGRoma, Italy
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P.O. "Andrea Tortora"
NOT_YET_RECRUITINGPagani, Italy
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