New drug combo shows promise for Tough-to-Treat breast cancer
NCT ID NCT07583485
First seen May 15, 2026 · Last updated May 15, 2026
Summary
This study tracks about 300 women with HER2-positive breast cancer that has spread. They receive a three-drug combination (tucatinib, capecitabine, trastuzumab) as part of their normal care. The goal is to see how well the treatment works and how safe it is in everyday medical practice, especially for patients who have already tried other therapies.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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A.O. "A. Cardarelli"
RECRUITINGNaples, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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A.O.U. "Città della Salute e della Scienza di Torino" - P.O. Sant'Anna
NOT_YET_RECRUITINGTorino, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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A.O.U. "San Giovanni di Dio e Ruggi d'Aragona"
NOT_YET_RECRUITINGSalerno, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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A.O.U. Policlinico "Umberto I"
NOT_YET_RECRUITINGRoma, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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A.O.U.P. "P. Giaccone"
ACTIVE_NOT_RECRUITINGPalermo, Italy
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A.S.L. Napoli 3 SUD - P.O. Apicella
NOT_YET_RECRUITINGPollena Trocchia, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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AORN "Sant'Anna e San Sebastiano" Caserta
RECRUITINGCaserta, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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AORN S.G. Moscati
RECRUITINGAvellino, AV, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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AOU Federico II
ACTIVE_NOT_RECRUITINGNaples, Italy
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AOU delle Marche
ACTIVE_NOT_RECRUITINGAncona, Italy
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ARNAS Civico - Palermo
NOT_YET_RECRUITINGPalermo, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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ASST Papa Giovanni XXIII
RECRUITINGBergamo, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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AUSL della Romagna - IRST-IRCCS "Dino Amadori"
RECRUITINGRimini, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Azienda Provinciale Servizi Sanitari di Trento - Ospedale Santa Chiara
NOT_YET_RECRUITINGTrento, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Casa Sollievo della Sofferenza
NOT_YET_RECRUITINGSan Giovanni Rotondo, Italy
Contact Email: •••••@•••••
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Fondazione Universitaria Policlinico Gemelli IRCCS
NOT_YET_RECRUITINGRoma, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Humanitas Istituto Clinico Catanese
RECRUITINGMisterbianco, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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I.R.C.C.S. Istituto Clinico Humanitas
NOT_YET_RECRUITINGRozzano, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Centro di Riferimento Oncologico (CRO)
RECRUITINGAviano, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Istituto Tumori "Giovanni Paolo II"
RECRUITINGBari, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Ospedale Policlinico San Martino
ACTIVE_NOT_RECRUITINGGenova, Italy
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IRCCS Ospedale San Raffaele
RECRUITINGMilan, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Istituto Europeo di Oncologia
RECRUITINGMilan, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Istituto Nazionale Tumori "Fondazione G. Pascale"
RECRUITINGNaples, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Istituto Oncologico Veneto I.R.C.C.S.
RECRUITINGPadova, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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La Maddalena
NOT_YET_RECRUITINGPalermo, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mons. Dimiccoli P.O. Barletta
NOT_YET_RECRUITINGBarletta, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale "Guglielmo Da Saliceto"
RECRUITINGPiacenza, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale "Sandro Pertini" - A.S.L. Roma 2
NOT_YET_RECRUITINGRoma, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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P.O. "Andrea Tortora"
NOT_YET_RECRUITINGPagani, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.