HER2-POSITIVE METASTATIC BREAST CANCER
Clinical trials for HER2-POSITIVE METASTATIC BREAST CANCER explained in plain language.
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New cancer drug enters first human trials for multiple tumor types
Disease control OngoingThis is the first human study testing the safety and early effects of an experimental drug called BL-M17D1 in people with advanced cancers that have a specific marker called HER2. The trial will enroll 120 adults with various hard-to-treat cancers, including breast, lung, and sto…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE1 • Sponsor: SystImmune Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug duo aims to control Tough-to-Treat breast cancer
Disease control OngoingThis study is testing whether combining two targeted drugs, tucatinib and alpelisib, can help control advanced HER2-positive breast cancer that has a specific genetic change (PIK3CA mutation). The first part checks the safety and best dose of the combination. The second part expa…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Criterium, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug tested for Tough-to-Treat breast cancer
Disease control OngoingThis study is testing an experimental drug called ARX788 for people with advanced HER2-positive breast cancer that has spread and has stopped responding to a previous targeted therapy. About 72 participants will receive ARX788 through an IV every three weeks to see if it can shri…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase: PHASE2 • Sponsor: Ambrx, Inc. • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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Doctors test exercise to predict heart risks in breast cancer treatment
Knowledge-focused OngoingThis study aims to understand how a special exercise test can help predict heart and lung function in women with HER2-positive breast cancer who are experiencing mild heart side effects from their treatment. Researchers will measure oxygen use during exercise in 23 participants w…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC