HER2-positive metastatic breast cancer
Clinical trials for HER2-positive metastatic breast cancer explained in plain language.
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PET scan could predict best drug sequence for advanced breast cancer
Disease control Stopped earlyThis study tests whether a special PET scan (HER2-PET) can help doctors decide which drug to use next in people with advanced HER2-positive breast cancer whose cancer has stopped responding to the drug trastuzumab deruxtecan (T-DXd). About 87 participants will get the scan and be…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase 2 • Sponsor: Jules Bordet Institute • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New drug cocktail shows promise for Hard-to-Treat breast cancer
Disease control Stopped earlyThis study tested a combination of three drugs—tucatinib, trastuzumab, and vinorelbine—in 13 people with HER2-positive breast cancer that had spread or could not be surgically removed. The goal was to see how many patients' tumors shrank or disappeared. The trial was terminated e…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase 2 • Sponsor: Spanish Breast Cancer Research Group • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC