HER2-positive metastatic breast cancer
Clinical trials for HER2-positive metastatic breast cancer explained in plain language.
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New drug cocktail targets breast cancer brain metastases
Disease control CompletedThis study tested a combination of three drugs (atezolizumab, pertuzumab, and high-dose trastuzumab) in 19 people with HER2-positive breast cancer that had spread to the brain. The goal was to see if the treatment could shrink or control brain tumors. While the approach aims to m…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase 2 • Sponsor: Nancy Lin, MD • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Can a targeted drug tame advanced HER2-Positive breast cancer?
Disease control CompletedThis study looks at how well trastuzumab deruxtecan (T-DXd) works and how safe it is in women with HER2-positive metastatic breast cancer. The drug is given as an intravenous infusion every three weeks to patients who have already tried other anti-HER2 treatments. Researchers wil…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Sponsor: Mansoura University • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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New drug targets Hard-to-Treat cancers in early trial
Disease control CompletedThis study tested a new drug called DF1001 in 270 adults with advanced solid tumors that have spread or cannot be removed. The drug works by helping the body's immune cells attack cancer cells. The trial first found the safest dose, then tested it alone or with other cancer drugs…
Matched conditions: HER2-POSITIVE METASTATIC BREAST CANCER
Phase 1/2 • Sponsor: Dragonfly Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC