HEAD AND NECK SQUAMOUS CELL CARCINOMA
Clinical trials for HEAD AND NECK SQUAMOUS CELL CARCINOMA explained in plain language.
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New combo therapy aims to keep head and neck cancer from coming back
Disease control Not yet recruitingThis study looks at whether adding the drug benmelstobart to standard treatment (radiation plus nimotuzumab) can help prevent head and neck cancer from returning after surgery. About 386 adults with intermediate-risk features will be randomly assigned to one of two groups. The ma…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University • Aim: Disease control
Last updated May 01, 2026 15:27 UTC
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Experimental combo aims to boost immune attack on Hard-to-Treat head and neck cancer
Disease control Not yet recruitingThis early-phase study tests a combination of two drugs—decitabine (a chemotherapy that can 'reawaken' genes) and nivolumab (an immunotherapy that helps the immune system fight cancer)—in people with head and neck cancer that has returned or spread and cannot be cured with local …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Kyunghee Burkitt, DO, PhD • Aim: Disease control
Last updated May 01, 2026 15:26 UTC
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Could adding radiation to immunotherapy before surgery boost cancer fight?
Disease control Not yet recruitingThis study tests whether adding radiation to immunotherapy before surgery helps people with advanced head and neck cancer. About 36 adults with treatable but advanced cancer will get either immunotherapy alone or with radiation, then have surgery. The goal is to see if the combin…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Chen Chunyan • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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Virus and chemo combo takes on hard-to-treat head and neck cancers
Disease control Not yet recruitingThis study tests a new combination for people with head and neck cancer that has come back or spread after at least two standard treatments. The approach uses a modified virus (H101) plus a targeted chemotherapy delivered directly to the tumor's blood supply (TACE) to kill cancer…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: West China Hospital • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New drug combo shows promise in shrinking head and neck tumors before surgery
Disease control Not yet recruitingThis study tests whether giving a new drug (becotatug vedotin) alone or with immune-boosting drugs before surgery can help shrink advanced head and neck cancer. About 120 adults with resectable tumors will receive the treatment before their operation. The main goal is to see if t…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: West China Hospital • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New radiation approach aims to cut side effects in head and neck cancer
Disease control Not yet recruitingThis study tests a shorter course of radiation (hypofractionated radiotherapy) for people with intermediate-risk head and neck cancer who have had surgery. The goal is to see if this approach is safe and effective at controlling the cancer while reducing long-term side effects. A…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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New drug cocktail shows promise in battle against head and neck cancer
Disease control Not yet recruitingThis study tests whether combining the immunotherapy drug camrelizumab with either an EGFR antibody or chemotherapy can help people with advanced head and neck cancer live longer. About 246 adults with stage III or IV cancer will receive the treatment before and after surgery. Th…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Yue He, MD • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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Glow-in-the-dark dye could help surgeons spot cancer during surgery
Diagnosis Not yet recruitingThis early-phase trial tests a fluorescent dye called ABY-029 that makes cancer cells glow during surgery. About 24 adults with head and neck cancer will receive a tiny dose of the dye before their tumor is removed. The goal is to find the right dose for clear imaging and to chec…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Diagnosis
Last updated May 01, 2026 15:25 UTC
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Blood test could spot hidden throat cancers before symptoms start
Diagnosis Not yet recruitingThis study will test if a simple blood test can find HPV-related throat cancer early in men aged 50 and older who have no symptoms. The test looks for two markers in the blood that signal the presence of the virus and cancer. If successful, this approach could lead to a national …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: UNICANCER • Aim: Diagnosis
Last updated Apr 30, 2026 15:52 UTC
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New radioactive antibody could light up Hard-to-Treat cancers
Diagnosis Not yet recruitingThis early-phase study tests a new radioactive antibody (NTH-2403) designed to find and attach to certain proteins on cancer cells. The goal is to see if it is safe and can help doctors see tumors more clearly using imaging. The study involves 16 adults with advanced colorectal, …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Radiopharm Theranostics, Ltd • Aim: Diagnosis
Last updated Apr 30, 2026 15:51 UTC