HEAD AND NECK SQUAMOUS CELL CARCINOMA
Clinical trials for HEAD AND NECK SQUAMOUS CELL CARCINOMA explained in plain language.
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New cancer drug RPH-002 tested against standard therapy in head and neck cancer trial
Disease control CompletedThis study tested a new drug called RPH-002 against the standard drug Erbitux in 118 people with advanced head and neck cancer that could not be removed by surgery. The goal was to compare how the drugs move through the body and check for side effects when given with chemotherapy…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: R-Pharm • Aim: Disease control
Last updated May 01, 2026 15:26 UTC
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AI-Powered radiation zaps only cancer, spares healthy tissue in head and neck trial
Disease control CompletedThis study tested a new way to give radiation for head and neck cancer. Instead of treating the whole neck, doctors used artificial intelligence to focus radiation only on the cancer and nearby suspicious spots. The goal was to see if this approach could control the cancer while …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated May 01, 2026 15:25 UTC
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New program helps cancer patients kick the habit
Disease control CompletedThis study tested a special smoking cessation program for people with head and neck or lung cancer. The program included counseling, medication, and nicotine replacement to help patients reduce smoking. Researchers wanted to see if cutting down could also change the tumor environ…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated May 01, 2026 15:25 UTC
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New combo therapy shows promise for tough cancers
Disease control CompletedThis study tested a new drug combination (IO102-IO103 plus pembrolizumab) as a first treatment for people with advanced lung, head/neck, or bladder cancer that had spread. The goal was to see if the combo could shrink tumors and delay cancer growth. A total of 63 patients took pa…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: IO Biotech • Aim: Disease control
Last updated May 01, 2026 15:23 UTC
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New immunotherapy combo shows promise for head and neck cancer patients
Disease control CompletedThis study tested whether adding the immunotherapy drug durvalumab to radiation therapy works better than the standard cetuximab plus radiation for people with advanced head and neck cancer who cannot take the chemotherapy drug cisplatin. The trial enrolled 196 participants and m…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 29, 2026 15:03 UTC
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New MRI technique may spot cancer recurrence early
Knowledge-focused CompletedThis study looked at whether a type of MRI called diffusion-weighted MRI can predict if head and neck cancer will return after chemoradiotherapy. Researchers followed 59 patients for up to a year after treatment. The goal was to see if early changes on the MRI could signal future…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated May 01, 2026 15:26 UTC
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Custom blood test could spot cancer return in head and neck patients
Knowledge-focused CompletedThis study looked at whether a personalized blood test can find tiny bits of tumor DNA (ctDNA) in 40 people with advanced head and neck cancer. The test was tailored to each patient's unique tumor mutations. Researchers checked blood before surgery, after surgery, and for 18 mont…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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Tumor samples stored to unlock personalized cancer predictions
Knowledge-focused CompletedThis study collected tumor samples from 419 adults with head and neck squamous cell carcinoma to create a biobank. The goal is to use these samples in future research to find genetic clues that can predict how the cancer will respond to treatment. By understanding these factors, …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Sponsor: Maastricht Radiation Oncology • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC