GRAFT VERSUS HOST DISEASE

This study tested whether using a lower dose of the drug cyclophosphamide after stem cell transplants could effectively prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The trial involved 35 adults with blood cancers wh…

This study tested whether the drug pomalidomide could help control chronic graft-versus-host disease (GvHD) in people who didn't respond to standard steroid treatments. GvHD is a serious complication that can occur after a stem cell transplant, where the donor's immune cells atta…

This study tested whether the drug nilotinib could help control chronic graft-versus-host disease in patients who had already tried and failed treatment with imatinib. The trial involved 65 adults who had received stem cell transplants and developed this serious complication wher…

This study tested whether Prochymal, a stem cell therapy, could help patients with severe graft-versus-host disease (GVHD) that hadn't responded to standard treatments. GVHD is a dangerous complication that can occur after a bone marrow transplant, where the donor cells attack th…

This study tested a new type of PET scan to see if it could find and predict Graft vs Host Disease (GVHD), a serious complication after a stem cell or bone marrow transplant. The scan uses a special tracer to highlight areas where certain immune cells are active, which is a sign …

This study tested if adding a new drug called BMS-986004 to standard anti-rejection medicine could safely prevent a serious complication called acute Graft-Versus-Host Disease (GVHD). It involved 45 patients with blood cancers who received a stem cell transplant from a donor. The…

This study tested if a special light-based blood treatment could prevent a serious complication called graft-versus-host disease (GVHD) in patients receiving a stem cell transplant for blood cancer. Researchers compared this treatment, which has milder side effects, to standard p…