Graft versus host disease
Clinical trials for Graft versus host disease explained in plain language.
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Fetal stem cells aim to tame immune chaos
Disease control Not yet recruitingThis early-stage trial tests clonal fetal mesenchymal stem cells (cfMSCs) in 100 people with severe immune-related disorders or tissue damage. The goal is to see if the cells are safe and can reduce symptoms. Participants have no other treatment options left.
Matched conditions: GRAFT VERSUS HOST DISEASE
Phase 1 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New study aims to cut Life-Threatening side effects in child leukemia transplants
Disease control Not yet recruitingThis large international study looks for better ways to manage stem cell transplants in children and young adults with high-risk or relapsed acute lymphoblastic leukemia (ALL). The goal is to reduce serious complications and long-term side effects while keeping the transplant's p…
Matched conditions: GRAFT VERSUS HOST DISEASE
Phase 2/3 • Sponsor: Bambino Gesù Hospital and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Can a new drug stop the Body's attack after stem cell transplants?
Prevention Not yet recruitingThis phase II trial tests whether adding axatilimab to standard care can prevent graft-versus-host disease (GVHD), a serious complication where donor immune cells attack the recipient's body after a stem cell transplant. Adults with blood cancers receiving a myeloablative allogen…
Matched conditions: GRAFT VERSUS HOST DISEASE
Phase 2 • Sponsor: Medical College of Wisconsin • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
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Scientists probe immune cells to unravel chronic GVHD mystery
Knowledge-focused Not yet recruitingThis study looks at why some people develop chronic graft-versus-host disease (GVHD) after a stem cell transplant. Researchers will collect blood, stool, saliva, and tissue samples from 75 participants to track immune cell changes over time. The goal is to better understand the d…
Matched conditions: GRAFT VERSUS HOST DISEASE
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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Can a simple supplement protect transplant patients? healthy volunteers pave the way
Knowledge-focused Not yet recruitingThis early-stage study tests whether healthy volunteers can regularly take two natural gut supplements, propionate and butyrate, which are normally made by the body. The goal is to see if this approach is safe and practical before trying it in patients receiving donor stem cell t…
Matched conditions: GRAFT VERSUS HOST DISEASE
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC