GASTROINTESTINAL CANCER

This study tested a new drug (TJ004309) combined with an approved immunotherapy (atezolizumab) in 25 people with advanced ovarian, head and neck, lung, gastrointestinal, or triple-negative breast cancers. The goal was to see if the combination could shrink tumors. Participants ha…

This early study tested a new drug called Cabotamig (ARB202) in 33 adults with advanced gastrointestinal cancers (like stomach, liver, or bowel cancer) that had stopped responding to standard treatments. The drug works by targeting a marker called CDH17 on cancer cells and helpin…

This early-stage study tested a new drug (BI 765049) alone or with another drug (ezabenlimab) in 21 Asian adults with advanced cancers like stomach, lung, or liver cancer that had stopped responding to treatment. The goal was to find a safe dose and see if the drugs could shrink …

This study tested a new treatment for people with advanced gastrointestinal cancers that had spread and stopped responding to standard therapies. Doctors took immune cells from each patient's tumor, used CRISPR gene editing to remove a gene called CISH that slows down the immune …

This study tested whether ultrasound can detect nerve damage caused by the chemotherapy drug oxaliplatin in people with gastrointestinal cancer. Twenty participants who had or were receiving oxaliplatin and had symptoms of nerve damage were enrolled. Researchers compared ultrasou…

This study tested a new program called BOLSTER, designed to give extra support to people with gynecologic or gastrointestinal cancers and their caregivers after a hospital stay. The program focused on helping patients manage complex care needs at home. The study measured whether …

This study tested a program called STRONG-PD that provides nutrition support remotely to people with gastrointestinal cancer that has spread to the lining of the abdomen. Ten participants who had surgery and chemotherapy used the program, which included a Fitbit and dietitian vis…

This study looked at whether adding oral nutrition supplements (like special drinks) to standard chemotherapy helps people with gastrointestinal cancer. 175 adults took part. The goal was to see if the supplements improve body composition, nutrition status, and quality of life, a…

This study tested whether silkworm pupa tablets can improve nutrition and reduce frailty in 120 people who had surgery for stomach, colorectal, esophageal, or pancreatic cancer. Participants took the tablets for 3 months, and researchers measured weight, muscle mass, and frailty.…

This study tested whether adding a palliative care team to standard surgeon-led care improves quality of life for patients undergoing major upper gastrointestinal cancer surgery. About 379 patients and their family members took part. The approach focused on co-managing symptoms a…

This study tested whether a simple walking program, using fitness trackers, helps cancer patients tolerate their daily chemotherapy and radiation treatments without missing doses. 166 adults with various cancers (brain, head/neck, lung, GI, or cervical) who were scheduled for cur…

This study looked at how to increase the number of patients who get DPYD testing before starting chemotherapy for gastrointestinal cancer. DPYD testing checks for gene changes that can cause severe or even deadly side effects from common chemo drugs. Researchers tested different …

This study looked at how 5-FU, a common chemotherapy drug, affects small blood vessels in the skin. Researchers measured blood flow in 62 people, including current and past cancer patients and healthy volunteers. The goal was to better understand why 5-FU can cause heart problems…

This study looked at whether having cancer patients report their own symptoms during radiation treatment helps doctors better understand and manage side effects. 104 adults with lung, esophageal, or other gastrointestinal cancers took part. Doctors reviewed patient-reported sympt…

This study looked at 100 adults with gastrointestinal cancer to see if having sarcopenia (muscle loss) changes how their body responds to muscle relaxants during surgery. Researchers used CT scans to group patients as sarcopenic or not, then measured how fast and deeply the muscl…

This study looked at how muscles use energy in undernourished patients with gastrointestinal cancer. The goal was to better understand the biological changes that cause severe weight loss and weakness. Researchers measured muscle cell energy production and fat content in 51 patie…