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Sarcopenia may change how muscle relaxants work during cancer surgery

NCT ID NCT07003061

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 100 adults having gastrointestinal cancer surgery to see if sarcopenia (muscle loss) changes how muscle relaxants work during anesthesia. Patients were grouped based on CT scans showing sarcopenia. The researchers measured how fast the relaxants worked, how deep the muscle relaxation was, and how long it lasted. The goal is to help doctors personalize anesthesia for safer surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help anesthesiologists adjust muscle relaxant doses for patients with sarcopenia, improving safety during surgery.
What could go wrong
This is a small observational study, not a treatment trial. It only measures effects during surgery and does not test any new drug or therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Jun 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 18 to 75 years who have been diagnosed with gastrointestinal cancer and are scheduled for elective surgery at Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. All participants will have undergone preoperative abdominal CT scans. Both male and female patients meeting the inclusion and exclusion criteria will be eligible for enrollment.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 18 and 75 years * Patients diagnosed with gastrointestinal system (GIS) cancer and scheduled for elective surgery * Patients who have undergone preoperative abdominal computed tomography (CT) imaging * Patients classified as American Society of Anesthesiologists (ASA) physical status I-III Exclusion Criteria: * Patients with a history of neuromuscular diseases * Patients receiving chronic steroid or immunosuppressive therapy * Patients with electrolyte imbalance * Patients using medications that affect neuromuscular transmission * Patients with severe organ failure in the preoperative period (e.g., liver or renal failure) * Patients who refuse to participate in the study * Patients requiring emergency surgery * Patients using muscle relaxants in the preoperative period

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Conditions

The condition(s) this trial relates to.

digestive system cancer digestive system neoplasm Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gastrointestinal cancer Neuromuscular blockade Sarcopenia

Contacts and locations

Locations

  • Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea

    Ankara, Yenimahalle, 06200, Turkey (Türkiye)

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