GASTROINTESTINAL CANCER

This study is testing whether daily postbiotic gummy supplements can help protect the balance of gut bacteria in people undergoing colon cancer surgery. Thirty patients scheduled for surgery will take either the postbiotic gummy or a placebo daily before and after their operation…

This study is testing an experimental drug called raludotatug deruxtecan for people with advanced cancers of the digestive system (like pancreatic, stomach, or colon cancer) that have spread or cannot be removed by surgery. The drug is designed to find cancer cells and deliver tr…

This study is testing if a drug called avatrombopag can help patients with gastrointestinal cancers who develop persistently low platelet counts from their chemotherapy. Low platelets can cause dangerous bleeding and force doctors to delay or reduce chemotherapy doses. About 60 p…

This study is testing a new radioactive imaging agent to see if it can help find cancers that produce a specific protein called CEA. Twenty patients with various CEA-positive cancers will receive the agent and undergo PET scans to see if it highlights their tumors. The goal is to…

This small, early-stage study is testing whether a guided therapy session using psilocybin (the active compound in 'magic mushrooms') can help reduce severe depression, anxiety, and emotional distress in people with advanced, incurable gastrointestinal cancers. The study involves…

This study is testing whether a simple chatbot on a patient's phone, combined with a Fitbit-like activity tracker, can help spot and manage symptoms from cancer treatment earlier. The goal is to see if this early warning system can help patients feel better and reduce unplanned t…

This study collects tumor tissue and blood samples from people with cancer to help researchers find new targets for future treatments. Participants are adults who are already having surgery or biopsy for their cancer care. No experimental treatments are given—researchers only col…

This study aimed to understand how often and what types of sleep problems occur in patients with gastrointestinal cancers before and after their surgery. Researchers planned to have patients fill out sleep questionnaires daily while in the hospital and wear activity trackers. The…

This study aims to understand if cancer patients from rural areas are more likely to be frail before major surgery compared to those from cities. Researchers will survey 100 patients, take a small blood sample, and review medical records to see if frailty scores predict who has m…

This study aims to better understand the real-world symptoms and treatment experiences of adults with certain cancers. About 100 participants with breast, lung, gastrointestinal cancer, or multiple myeloma will complete weekly digital surveys about their symptoms for at least 12 …

This study looks back at medical records to understand how well immunotherapy cancer drugs work for American Indian patients compared to White patients. Researchers will analyze survival times, side effects, and cancer-related deaths in 72 patients who were treated between 2015 a…

This study collects blood and tumor cells from cancer patients and blood from healthy volunteers. The cells are used in the lab to support research into future immune cell therapies for cancers like melanoma, breast cancer, and lung cancer. No treatment is given in this study; it…

This study is testing a new training program for nurses called PACT. The goal is to see if it helps nurses better support family members who are caring for loved ones with advanced gastrointestinal cancer in the hospital. Researchers will observe how often nurses use these new sk…