EYE DISEASES
Clinical trials for EYE DISEASES explained in plain language.
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Eye drop may stop eyelash regrowth after trachoma surgery
Disease control CompletedThis study tested whether a steroid eye drop (fluorometholone) given twice daily for four weeks after trachoma surgery could stop eyelashes from growing back and rubbing against the eye. Over 2,400 people with trachomatous trichiasis took part. The goal was to see if the drops ar…
Matched conditions: EYE DISEASES
Phase: PHASE3 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated May 26, 2026 09:38 UTC
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New lens sharpens vision for cataract patients with astigmatism
Disease control CompletedThis study tested a new type of lens implant (PODEYE TORIC) for people having cataract surgery who also have astigmatism (blurry vision from an irregularly shaped cornea). The lens aims to correct both the cataract and the astigmatism at the same time. 261 adults received either …
Matched conditions: EYE DISEASES
Sponsor: Beaver-Visitec International, Inc. • Aim: Disease control
Last updated May 26, 2026 09:34 UTC
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Experimental eye injection targets rare Blindness-Causing gene
Disease control CompletedThis early-stage study tested a new drug called VP-001 in 6 people with a rare inherited eye disease caused by a PRPF31 gene mutation. The drug was given as an injection into the eye to see if it is safe and tolerable. The goal was to check for side effects, not to measure if it …
Matched conditions: EYE DISEASES
Phase: PHASE1 • Sponsor: PYC Therapeutics • Aim: Disease control
Last updated May 26, 2026 09:32 UTC
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New antibody shows promise for thyroid eye disease in early trial
Disease control CompletedThis study tested a new drug called LASN01 in 41 adults with moderate-to-severe thyroid eye disease (TED). The drug is an antibody that blocks a protein involved in inflammation. The goal was to see if it could reduce eye bulging and other symptoms safely. Participants received e…
Matched conditions: EYE DISEASES
Phase: PHASE2 • Sponsor: Lassen Therapeutics Inc. • Aim: Disease control
Last updated May 26, 2026 09:26 UTC
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Nurse-Led online eye test could save Seniors' sight at home
Diagnosis CompletedThis study tested whether a nurse-assisted online eye screening at home is cost-effective for older adults receiving home healthcare. 234 participants aged 65+ were included. The goal was to see if this approach reduces eye complaints and detects vision changes early.
Matched conditions: EYE DISEASES
Phase: NA • Sponsor: Amsterdam UMC, location VUmc • Aim: Diagnosis
Last updated May 18, 2026 12:02 UTC
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New eye drops show promise for aging eyes in Long-Term safety trial
Symptom relief CompletedThis study tested the long-term safety of LNZ101 eye drops for presbyopia, a common age-related condition that makes it hard to see things up close. A total of 362 adults aged 45 to 75 took part. The main goal was to check for side effects related to the treatment.
Matched conditions: EYE DISEASES
Phase: PHASE3 • Sponsor: LENZ Therapeutics, Inc • Aim: Symptom relief
Last updated May 26, 2026 09:40 UTC
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New eye drop could replace reading glasses for millions
Symptom relief CompletedThis study tested an eye drop called LNZ101 to improve near vision in people with presbyopia, an age-related condition that makes it hard to see close up. 229 adults aged 45-75 took part. The main goal was to see if the drop could give a big improvement in reading vision without …
Matched conditions: EYE DISEASES
Phase: PHASE3 • Sponsor: LENZ Therapeutics, Inc • Aim: Symptom relief
Last updated May 26, 2026 09:37 UTC
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New eye drops may replace reading glasses for millions
Symptom relief CompletedThis study tested an eye drop called LNZ101 to help people with presbyopia, an age-related condition that makes it hard to see things up close. 469 adults aged 45-75 took part. The main goal was to see if the drops could improve near vision by at least 3 lines on an eye chart wit…
Matched conditions: EYE DISEASES
Phase: PHASE3 • Sponsor: LENZ Therapeutics, Inc • Aim: Symptom relief
Last updated May 26, 2026 08:20 UTC
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Breath test could replace needles for monitoring anesthesia in kids
Knowledge-focused CompletedThis study checked if the amount of propofol (an anesthesia drug) in children's breath matches the amount in their blood during eye surgery. 32 children having planned eye surgery took part. Researchers compared breath measurements with blood samples and brain activity monitors. …
Matched conditions: EYE DISEASES
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 09:42 UTC
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Eye-Opener: stanford tests supplement absorption in aging eyes
Knowledge-focused CompletedThis early-stage study at Stanford looked at how a nutritional supplement called alpha-ketoglutarate is absorbed into the eyes of people with age-related eye diseases. 17 participants took the supplement by mouth, and researchers measured changes in eye fluid and proteins. The go…
Matched conditions: EYE DISEASES
Phase: EARLY_PHASE1 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 26, 2026 09:37 UTC
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AI eye exam: 2,000 patients test machine vs. doctor
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can help diagnose eye diseases like cataracts and glaucoma. Researchers compared AI's accuracy and speed to that of eye doctors using 2,000 patient cases. The goal was to see if AI could support or improve eye care.
Matched conditions: EYE DISEASES
Sponsor: North Sichuan Medical College • Aim: Knowledge-focused
Last updated May 26, 2026 08:19 UTC
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New tool could help doctors decide when to operate on Babies' eyes
Knowledge-focused CompletedThis study tested a new questionnaire designed to measure how well babies (0-36 months old) with eye diseases can see, even before they can talk. The goal was to see if the questionnaire is reliable and accurate, so doctors can better decide when surgery is needed. The study incl…
Matched conditions: EYE DISEASES
Phase: NA • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Eye camera reveals hidden clues to multiple sclerosis progression
Knowledge-focused CompletedThis study tested a special eye-imaging technique called adaptive optics to look at blood vessel changes in the retina of people with multiple sclerosis (MS). Researchers measured swelling around retinal vessels in 50 participants with different MS types and compared them to heal…
Matched conditions: EYE DISEASES
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC