EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Clinical trials for EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION explained in plain language.
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Blood thinner showdown: could bivalirudin be safer for ECMO patients?
Disease control Recruiting nowThis study tests whether bivalirudin, a blood thinner, works better and causes fewer side effects than the standard drug heparin for patients on ECMO (a machine that helps the heart and lungs). About 154 adults on ECMO will be randomly assigned to receive either drug. The goal is…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Xiaotong Hou • Aim: Disease control
Last updated May 26, 2026 08:50 UTC
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Can a Heart-Lung machine save kids with deadly sepsis?
Disease control Recruiting nowThis study looks at whether a machine called ECMO can help children with severe septic shock who are not getting better with standard care. ECMO acts like an artificial heart and lungs to support the body. The study will include 60 children and track how many survive after leavin…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated May 26, 2026 08:45 UTC
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New blood thinner could make Heart-Lung machines safer after surgery
Disease control Recruiting nowThis study compares a drug called nafamostat mesilate to the standard blood thinner heparin in 80 adults who need a heart-lung machine (ECMO) after heart surgery. The goal is to see if nafamostat prevents dangerous blood clots as well as heparin, but with fewer bleeding complicat…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Xiaotong Hou • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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ECMO blood thinner showdown: which drug wins?
Disease control Recruiting nowThis study tests two blood thinners, bivalirudin and heparin, in 80 adults on ECMO (a machine that helps the heart and lungs). The goal is to see which drug keeps blood thin enough to prevent clots without causing dangerous bleeding. Participants are randomly assigned to one of t…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE2 • Sponsor: Sydney Local Health District • Aim: Disease control
Last updated May 26, 2026 08:33 UTC
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Heart rescue: can Power-Packing cells save kids on life support?
Disease control Recruiting nowThis study tests a new approach to help children under 18 who are on ECMO (a heart-lung machine) and have heart muscle damage. Doctors will inject the child's own mitochondria (the energy parts of cells) directly into the heart to see if it helps the heart recover and allows the …
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated May 26, 2026 08:30 UTC
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Can resting the lungs on ECMO save more lives? major trial launches
Disease control Recruiting nowThis study tests a new approach for people with severe lung failure (ARDS) who are on a life-support machine called ECMO. Instead of giving small breaths, doctors will temporarily stop all breathing support to let the lungs rest completely. The goal is to see if this reduces lung…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 22, 2026 13:49 UTC
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New trial aims to cut deadly complications in Life-Support machine
Knowledge-focused Recruiting nowThis study looks at how to reduce major complications and improve survival for people on ECMO, a machine that helps the heart and lungs when they fail. Researchers will compare different treatments in 600 adults to see which ones lead to better outcomes, like needing less organ s…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE3 • Sponsor: Australian and New Zealand Intensive Care Research Centre • Aim: Knowledge-focused
Last updated May 26, 2026 08:29 UTC
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New mini lung machine tested on smallest patients
Knowledge-focused Recruiting nowThis study is testing a new device called the MiniLung petite kit in 20 newborns and children weighing 2 to 8 kilograms who have severe breathing or heart failure. The device is used with a machine that takes over the work of the lungs and heart (ECMO). Researchers want to see if…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Sponsor: Xenios AG • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Could ECMO work without blood thinners? new study aims to find out.
Knowledge-focused Recruiting nowThis study is testing whether a machine that helps severely damaged lungs (ECMO) can be run safely without using blood thinners. Blood thinners are normally used to prevent clots, but they can cause dangerous bleeding. The study will enroll 40 adults with severe lung failure who …
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE2, PHASE3 • Sponsor: Damian Ratano • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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New monitor could save limbs of sedated ECMO patients
Knowledge-focused Recruiting nowThis study tests a new device that continuously measures pressure in the leg to detect a dangerous condition called compartment syndrome in patients on ECMO. Because these patients are sedated and can't report symptoms, early detection is hard. The study compares three methods to…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC
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Massive ICU trial aims to find best treatments for lung failure
Knowledge-focused Recruiting nowThis large, ongoing study tests several treatments for patients with severe breathing failure (acute hypoxemic respiratory failure). It includes up to 6,250 adults in the ICU who need oxygen or a breathing machine. The goal is to find which treatments—like different ventilator se…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 19, 2026 12:00 UTC