ELDERLY

This study compares two seasonal flu vaccines—one with an added immune booster (adjuvanted) and one without—in adults aged 65 and older who have at least one chronic medical condition like diabetes or heart disease. The goal is to see which vaccine triggers a stronger immune resp…

This study looks at whether using a positive airway pressure (PAP) machine at night can improve thinking, sleepiness, and quality of life in older veterans (age 60+) who have both COPD and obstructive sleep apnea—a combination called Overlap Syndrome. About 668 participants will …

This study tests whether a team of specialists—including surgeons, oncologists, and geriatricians—can create better treatment plans for elderly lung cancer patients. 2,000 people aged 60-90 will receive personalized care based on their overall health and cancer type. The goal is …

This study tests whether metformin, a diabetes drug, can improve mild memory and thinking problems in older adults who are overweight or obese. Fifty-four participants will receive either metformin plus lifestyle advice or lifestyle advice alone for 26 weeks. Researchers will use…

This study tests whether giving elderly patients with kidney disease a personalized amount of fluids, guided by a lung water monitor, can prevent acute kidney injury after coronary angiography. About 320 participants aged 60 and older will receive either tailored hydration or sta…

This early-stage study tests whether a combination of two experimental drugs, GI-102 and GIB-7, can improve immune function and other signs of aging in healthy adults and cancer survivors. The trial involves 15 participants and lasts 8 weeks, focusing on safety and changes in imm…

This study looks at two ways to treat a specific type of neck fracture (odontoid fracture) in people aged 70 and older. Participants will be randomly assigned to either surgery or wearing a rigid neck collar. The goal is to see which treatment helps them recover better in daily a…

This study looks at whether singing—alone or in a group—can improve heart health in older adults with coronary artery disease. Researchers will test if people stick with the program and if it's practical to run a larger trial. The study involves 32 participants who will sing thre…

This study tests a friendly AI chatbot that guides people through telling their life stories to improve emotional well-being and sense of identity. It includes healthy adults, adults with mental health conditions in residential care, and healthy seniors aged 65+. The chatbot is n…

This study looks at whether adding local muscle vibration to standard rehabilitation can help elderly patients (75+) recover muscle strength and mobility after hip fracture surgery. The treatment involves 30-minute vibration sessions, 5 times a week for 4 weeks. The main goal is …

This study looks at whether a blood test for a protein called p-tau181 and brain scans can predict which elderly patients with dementia, frailty, and loss of independence will need to visit the emergency room within six months. Researchers will follow 110 participants and track E…

This study looks at whether it is safe to stop antibiotics early in elderly patients (65+) hospitalized for a viral lung infection. Many patients get antibiotics even when they have a virus, which can cause side effects and lead to antibiotic resistance. Researchers will compare …

This study looks at why some older adults get stronger from exercise while others don't. Researchers will track 900 people aged 60+ to measure muscle power and blood markers. The goal is to learn how to personalize physical activity plans for better results in seniors.

This study looks at people over 60 who had a stroke linked to a common heart hole called PFO. It compares three treatments: closing the hole, taking blood thinners, or using antiplatelet drugs. The goal is to see which option best prevents another stroke. About 400 older adults w…

This study is watching 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like confusion (delirium). Researchers will collect blood samples and health information to build a tool that predicts these risks. The goal is to better understa…

This study looks at how well the body uses protein from peas in healthy young and older adults who are either vegetarian or eat meat. Researchers want to see if age or diet changes how plant proteins are digested. The results will help create better nutrition advice for older peo…

This study looks at whether elderly men (70+) with prostate cancer who have been on hormone therapy for over 3 years can safely stop it. Researchers will check if their testosterone stays at castrate levels without ongoing treatment. The goal is to see if stopping is feasible and…