DYSLIPIDEMIA

This study tested a drug called Cipros 10 in 146 adults with high cholesterol and triglycerides. The goal was to see if it safely lowers blood fat levels. Participants took the medication or a placebo for a set period, and doctors measured changes in triglycerides and watched for…

This study tested whether a specific combination of food supplements could help middle-aged adults (over 45) who are overweight feel fuller and improve their cholesterol and blood sugar levels. Over 12 weeks, 80 participants either took the supplements or a placebo. The goal was …

This study tested a lifestyle program designed for Native Hawaiian and Pacific Islander adults with conditions like diabetes, high blood pressure, and obesity. Community health workers delivered the program, which included support for social needs like housing and food access. Th…

This study tested an experimental drug called ALN-APOC3 in 32 adults with dyslipidemia (abnormal levels of fats in the blood). The main goal was to check the drug's safety and how the body processes it. Researchers also looked at how the drug changes cholesterol and other fat lev…

This pilot study tested two health coaching strategies for Black adults with stage 1 obesity and conditions like high blood pressure, prediabetes, or high cholesterol. One strategy focused on weight loss, while the other focused on increasing physical activity without targeting w…

This study tested a drug called MCI-196 in 642 adults on dialysis who had high phosphorus and cholesterol levels. Participants took either MCI-196 or a placebo for 12 weeks to see if the drug could safely lower both phosphorus and LDL cholesterol. The goal is to help manage heart…

This early-stage study tested a new drug called AZD0780 in 81 healthy adults with high LDL (bad) cholesterol. Participants took AZD0780 or a placebo on top of standard cholesterol medicines like ezetimibe, rosuvastatin, or bempedoic acid. The main goals were to see how well the c…

This study tested a new daily medication called AZD0780 in 428 adults with high cholesterol. Participants took one of several doses of the drug or a placebo for 12 weeks to see how well it lowered their bad (LDL) cholesterol. The goal was to find out if AZD0780 is safe and effect…

This phase 3 trial tested whether combining two drugs, JW0108 and C2407, can safely lower LDL (bad) cholesterol in people with dyslipidemia. 145 adults took part. The main goal was to see how much LDL cholesterol dropped from the start of the study. The trial is now complete.

This study looked at 40 adults to see if high levels of lipoprotein (a), a fatty substance in the blood, affect the number of stem cells that repair blood vessels. Researchers compared people with high and normal levels of this substance. The goal was to better understand how lip…

This study looked at how fat particles called lipoproteins travel in the blood. Researchers wanted to better understand normal and abnormal fat metabolism and its link to hardening of the arteries. About 759 healthy volunteers and people with cholesterol disorders took part. Part…

This early-stage study tested a single shot of HRS-5632 in 50 healthy adults to see if it is safe and how the body processes it. The goal was not to treat any disease, but to gather important safety and drug-level information for future studies. Participants were healthy voluntee…