DIABETE MELLITUS

This early-stage study tests a new treatment called SR-02 for adults with type 1 diabetes who have severe low blood sugar episodes. The treatment involves implanting insulin-producing cells into the belly lining. Participants will need to take lifelong immune-suppressing drugs to…

This study tests a digital tool called "Smart family doctor" that uses artificial intelligence to help patients manage their blood pressure, blood sugar, and cholesterol after heart surgery or stent placement. About 951 adults who have had bypass surgery or a stent and also have …

This study tests a new procedure that uses electrical pulses to rejuvenate the lining of the first part of the small intestine (duodenum) in people recently diagnosed with type 2 diabetes. The goal is to see if this can help control blood sugar and possibly allow participants to …

This study tests whether adding a new drug called DA-2811 to standard diabetes medications helps people with type 2 diabetes who still have high blood sugar. About 288 adults will be randomly assigned to receive either DA-2811 or a placebo, and researchers will measure changes in…

This study tests a 12-week program where people with type 2 diabetes and a family member receive diabetes education and quizzes via WhatsApp. The goal is to see if this approach improves blood sugar control, self-care, and family support compared to usual care. The study involves…

This study will test whether regular phone calls from a nurse can help adults with diabetes in Ethiopia improve their blood sugar control, take their medication as prescribed, and learn more about managing their disease. About 320 patients from three hospitals will either receive…

This study aims to create an AI-based system that helps people with diabetes spot early warning signs of foot ulcers returning. Researchers will enroll 200 adults with healed diabetic foot ulcers and use a home monitoring tool to track their feet. The goal is to catch recurrences…

This study tests a new medicine called DA-5218 for people with type 2 diabetes whose blood sugar is still too high despite taking metformin. About 238 adults will receive either DA-5218 or another active drug to see which better lowers HbA1c (a measure of blood sugar control over…

This study tests whether a supplement called tributyrin can improve blood sugar control, reduce inflammation, and lower heart disease risk in people with type 2 diabetes. About 60 adults with diabetes and moderate-to-high heart risk will take either tributyrin plus their usual tr…

This study tests whether a common diabetes medication (a DPP4 inhibitor) can improve thinking and memory after a mild stroke in people with type 2 diabetes. About 312 adults aged 40-75 will take either the drug or a placebo for 180 days. The goal is to see if the drug reduces the…

This study compares silicone pads to felted foam for reducing pressure under the foot in people with diabetes and nerve damage who are at high risk of foot ulcers. About 80 participants will wear each type of pad, and researchers will measure how well they lower pressure and how …

This study tests a new way to detect early damage in the feet of people with diabetes. By measuring how the skin on the bottom of the foot responds to pressure, researchers hope to identify those at risk for foot ulcers before they develop. The study will include 200 adults with …

This study looks at how well nerve tests and ultrasound can detect nerve damage in people with diabetes. Researchers will compare results from diabetic patients and healthy volunteers to find better ways to diagnose diabetic peripheral neuropathy early. The goal is to improve man…

This study tests whether giving a salbutamol inhaler during surgery can prevent lung collapse (atelectasis) in diabetic patients after chest, belly, or spine surgery. About 80 adults aged 18-70 with well-controlled health will be enrolled. Researchers will check vital signs, ches…

This study tests a simple color rotation training technique to help people with diabetes better manage their insulin injections. Researchers will teach 112 adults who use insulin four times a day a color-based system to organize their shots. The goal is to see if this method impr…

This study aims to find a better way to prepare for colonoscopy in people with diabetes. Standard prep often causes low blood sugar and poor bowel cleaning. The new approach uses a low-fiber diet the day before and same-day preparation to reduce risks and improve results. About 4…

This study will check heart disease risk in 238 adults with type 2 diabetes using standard risk scores. It will also see if simple belly fat measurements can predict that risk. The goal is to find a better way to identify high-risk patients early.

This study will measure levels of a specific thyroid antibody (anti-thyroglobulin) in 112 adults with diabetes. The goal is to better understand how often thyroid autoimmunity occurs in people with diabetes. Participants will provide a blood sample, and those with a history of th…

This study aims to see if common blood tests can help predict how severe a heart attack is and what the recovery might look like, especially for people with diabetes. Researchers will follow 1,000 patients who have a specific type of heart attack (STEMI) and are treated with a pr…

This study looks at whether a special program called HEARTS-D can help health clinics in Nigeria better find and treat diabetes. About 2,800 adults with or at risk for diabetes will take part. The goal is to see if more people get screened and treated for diabetes over time.

This study will track menstrual cycles in 110 teenage girls (ages 10-18) with and without diabetes to see how diabetes affects period regularity. Researchers will also check if blood sugar control and body weight are linked to menstrual problems. The goal is to better understand …

This early-stage study will give 100 healthy volunteers one of three statins (atorvastatin, rosuvastatin, or simvastatin) for two days to see how their blood sugar, insulin, and C-peptide levels change. The goal is to understand if these cholesterol-lowering drugs can temporarily…