DIABETE MELLITUS

This study is testing the safety of the FreeStyle Libre 2, a flash glucose monitoring system, in 550 children and young adults aged 4 to 30 with type 1 or type 2 diabetes. The goal is to see if using this device lowers the rate of severe low blood sugar events that need medical h…

This study compares two wound treatments for people with diabetes who have severe foot wounds after leg artery surgery. One group gets standard vacuum therapy, the other gets vacuum therapy plus a silver nanoparticle spray. The goal is to see which approach helps wounds close fas…

This study compares two types of anesthesia in 60 diabetic adults having video-assisted chest surgery. One method uses only IV drugs (TIVA), the other uses inhaled gas. Researchers want to see which keeps blood sugar more stable and causes fewer side effects like nausea or pain.

This study looks at whether referring lonely older adults with diabetes to a social worker can help lower their blood sugar (A1C) and reduce loneliness. About 90 seniors will either meet with a social worker or continue their usual care. Researchers will check A1C from medical re…

This study tests whether linaclotide, a drug for constipation, can help people with type 2 diabetes who also have chronic constipation. About 23 participants will receive either the drug or a placebo for two weeks, then switch after a break. The goal is to see if the drug increas…

This study tests whether a gel made from a patient's own platelets can speed up healing and reduce pain after tooth extraction in people with diabetes. Twelve diabetic adults who need two similar teeth removed will have one socket treated with the gel and the other left untreated…

This study tests two types of nerve-gliding exercises—active (done by the patient) and passive (done by a therapist)—in 60 adults aged 40–65 with diabetic neuropathy. The goal is to see which method better reduces burning pain, improves muscle strength, and increases joint moveme…

This study aimed to see if using wearable devices and game-like features could encourage hospital patients with heart conditions to walk more. It was designed for adults aged 50 and older admitted to medicine or cardiology floors. However, the study was withdrawn before any parti…

This study looks at whether certain substances in the blood can predict deep wound infections after open-heart surgery. Researchers will track 30 patients who already have a deep sternal wound infection to see which blood markers change before and after surgery. The goal is to us…

This study looks at heart and metabolic problems in people with biochemically silent pheochromocytomas and paragangliomas (rare adrenal tumors that don't produce excess hormones). Researchers will measure blood pressure, heart function, and metabolic markers before and after surg…