DEVELOPMENTAL DISABILITY

This study tests whether metformin, a diabetes medication, can help adults with intellectual disability who have gained weight from antipsychotic drugs. About 100 participants will receive either metformin or a placebo for several months. The goal is to see if metformin leads to …

This study looks at whether a 12-week early intervention program can help improve social communication in preschoolers with developmental disorders like autism. The program involves 12 hours per week of intensive activities either at a center or at home. Researchers will measure …

This study tests a personalized approach to reduce problem behaviors like aggression and screaming in children up to 5 years old who have developmental delays. Researchers will work with parents and early intervention professionals to design and implement a function-based behavio…

This study tests whether a mixed-reality video game called Bootle Blast can help children with cerebral palsy improve their arm and hand skills when used at home. About 46 children aged 6-17 with hemiplegic cerebral palsy will either start the game right away or wait 12 weeks whi…

This study tests two group training programs for parents or caregivers of children aged 0-12 who have disruptive behavior or developmental delays. The programs teach behavior management techniques to reduce problem behaviors and lower parenting stress. About 800 English- or Spani…

This study aims to understand how different types of brain damage (from stroke, tumors, or diseases) cause specific problems with thinking, memory, and other mental skills. Researchers will use advanced brain scans and cognitive tests in 400 adults (both with and without brain in…

This study looks at whether hand and arm tests for children with cerebral palsy can be done effectively over video calls instead of in person. About 100 kids aged 6 to 17 will try both virtual and in-person assessments to see if the results match up. The goal is to make care more…

This study looks at how a robotic walking trainer called Trexo helps people with physical disabilities, like cerebral palsy, improve their walking. Researchers want to understand why it works and how to make it better. About 50 participants will try different settings on the robo…

This study looks at a special clinic called the Transitional and Lifelong Care (TLC) program, designed for adults with conditions like cerebral palsy, spina bifida, or developmental disabilities that started in childhood. The goal is to see if this clinic helps patients and their…

This study tests whether a one-time online lesson can improve how researchers think about and include people with disabilities in their studies. About 200 researchers will take the course, and their knowledge and attitudes will be measured before and after. The goal is to make re…