DEPRESSION, ANXIETY
Clinical trials for DEPRESSION, ANXIETY explained in plain language.
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Kenya study shows group loans and therapy boost HIV treatment success
Disease control CompletedThis study tested a program that combines group savings and loans with education on parenting, farming, and mental health support for people with HIV in Kenya. The goal was to help them stick to their HIV medication, lower stress, and achieve undetectable virus levels. Over 800 p…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Phone-Based support cuts HIV risk and boosts mental health in romanian men
Prevention CompletedThis study tested whether mobile counseling could help Romanian gay and bisexual men reduce HIV risk and improve mental health. 300 men completed surveys and 8 online sessions with a counselor or by reading health information. The program aimed to lower risky sex and heavy drinki…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Columbia University • Aim: Prevention
Last updated May 26, 2026 11:20 UTC
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Ketamine shows promise for Post-Surgery depression in brain pressure patients
Symptom relief CompletedThis study looked at whether a single dose of ketamine can reduce depressive symptoms in adults undergoing a specific type of brain surgery (lumbo-peritoneal shunt insertion). The trial involved 110 participants aged 20-44 with moderate to severe depression. Researchers measured …
Matched conditions: DEPRESSION, ANXIETY
Phase: PHASE4 • Sponsor: Benha University • Aim: Symptom relief
Last updated May 26, 2026 11:26 UTC
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Online therapy shows promise for Gut-Brain troubles
Symptom relief CompletedThis study tested a new online program (iACTforDGBI) for people with disorders of the gut-brain interaction, like irritable bowel syndrome, who also have anxiety or depression. 27 participants tried the self-guided sessions and gave feedback through interviews and questionnaires.…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Örebro University, Sweden • Aim: Symptom relief
Last updated May 26, 2026 11:24 UTC
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Can a resilience program ease cancer-related anxiety in young adults?
Symptom relief CompletedThis study tested whether a program called PRISM (Promoting Resilience in Stress Management) is practical and helpful for young adults aged 18-39 who have been diagnosed with cancer or desmoid tumors. The program aims to reduce symptoms of depression and anxiety. Researchers enro…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated May 26, 2026 11:23 UTC
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Laughter yoga may ease depression and stress in dialysis patients
Symptom relief CompletedThis study tested whether online laughter therapy could improve mood and quality of life in 69 adults on hemodialysis. Participants did laughter yoga sessions online, and researchers measured depression, anxiety, stress, and quality of life. The goal was to see if this simple, gr…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Zonguldak Bulent Ecevit University • Aim: Symptom relief
Last updated May 26, 2026 11:20 UTC
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Can the metaverse help treat depression? new study says maybe.
Symptom relief CompletedThis study tested a new cognitive-behavioral skills training program delivered in the metaverse for people with depression and anxiety. 306 participants were split into three groups: one using virtual reality, one using a flat-screen computer, and one waiting 8 weeks before start…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Can a smartphone app ease anxiety in breast cancer survivors?
Symptom relief CompletedThis study tested a mobile app called IntelliCare to help breast cancer survivors with depression and anxiety. 313 women who had been diagnosed within the past 5 years and had elevated symptoms used the app or received standard educational materials. The study also explored wheth…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Heart surgery patients get mood boost from single drug dose
Symptom relief CompletedThis study looked at whether giving a single dose of esketamine, a drug related to ketamine, could help reduce anxiety and depression in people having heart valve surgery. 142 adults took part, and researchers measured their mood before and after surgery using standard questionna…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Chinese PLA General Hospital • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Can online therapy or mindfulness quiet the ringing in your ears?
Symptom relief CompletedThis study tested two online programs—cognitive behavioral therapy (CBT) and mindfulness—to help adults cope with the distress caused by tinnitus (ringing in the ears). 67 participants were randomly assigned to CBT, mindfulness, or a waiting list. Both online treatments were foun…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Vilnius University • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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Can a phone app ease burnout for doctors? new study says maybe.
Symptom relief CompletedThis study tested a digital well-being program for 293 doctors at Penn Medicine during the COVID-19 pandemic. The program included text messages, resource support, and peer groups. Researchers measured changes in depression, anxiety, stress, and job satisfaction. The goal was to …
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Head light therapy shows promise for depression relief
Symptom relief CompletedThis study tested a new, non-invasive light therapy called transcranial photobiomodulation (tPBM) for people with major depression. 50 adults received either active light or a sham treatment on their forehead three times a week for six weeks. The goal was to see if this light the…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: NeuroThera DE • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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Virtual reality headsets may curb PTSD in lung transplant patients
Symptom relief CompletedThis study tested whether virtual reality therapy could prevent anxiety, depression, and PTSD in adults who had a lung transplant. 62 patients used a VR headset with scenes that gradually increased stress, like ICU alarms, to help them get used to the environment. The goal was to…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Symptom relief
Last updated May 19, 2026 12:01 UTC
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Talking through problems eases caregiver stress, study finds
Symptom relief CompletedThis study tested a problem-solving therapy program for family caregivers of people with cancer who were receiving palliative care. Over 500 caregivers took part, and researchers measured changes in anxiety and depression symptoms. The goal was to see if learning practical proble…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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New web tool boosts therapy homework for anxiety and depression
Symptom relief CompletedThis study tested a simple web platform called Adhere.ly that helps therapists encourage clients to practice therapy skills between sessions (homework). 79 adults with anxiety or depression and their therapists took part. The goal was to see if using the tool improved symptoms an…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated May 11, 2026 20:39 UTC
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New online therapy for Gut-Brain issues shows promise in small study
Knowledge-focused CompletedThis study tested a new online program (iACTforDGBI) for people with disorders of the gut-brain interaction, like IBS, who also have anxiety or depression. 30 patients tried the self-guided sessions and gave feedback through interviews and questionnaires. The goal was to see if t…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Örebro University, Sweden • Aim: Knowledge-focused
Last updated May 26, 2026 11:28 UTC
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Can a cultural training program help communities respond to mental health crises?
Knowledge-focused CompletedThis study tested a training program called First Face, designed to help community members recognize and respond to mental health crises. 92 staff from the Healing Lodge of the Seven Nations took surveys before, right after, and 3 months after training. The goal was to see if the…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Cambridge Health Alliance • Aim: Knowledge-focused
Last updated May 26, 2026 11:16 UTC
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Cash for therapy: study tests if money gets students to open up
Knowledge-focused CompletedThis study looked at whether offering cash rewards and mental health screening can encourage college students in Chennai, India, to seek therapy. 340 women students took part. Some students received information about their mental health risk, some were offered money for their fir…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Massachusetts Institute of Technology • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Pandemic disrupted chronic disease care for nearly 1 million canadians
Knowledge-focused CompletedThis study analyzed health records from nearly 1 million Canadian adults to see how the COVID-19 pandemic affected primary care for chronic conditions like diabetes, heart failure, and depression. Researchers looked at changes in doctor visits, tests, and treatments before and du…
Matched conditions: DEPRESSION, ANXIETY
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Chilean study tracks chronic Pain's toll on mental health and daily life
Knowledge-focused CompletedThis study followed over 2,300 adults from urban areas of Chile for one year to learn more about chronic pain and its effects. Researchers measured pain levels, mental health issues like depression and anxiety, and how pain impacted work and social life. The goal was to better un…
Matched conditions: DEPRESSION, ANXIETY
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated May 19, 2026 11:46 UTC
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Foster parent program aims to curb mental health crisis in rural and minority youth
Knowledge-focused CompletedThis study looked at a program called KEEP that trains foster and kinship parents to better support children in their care. The goal was to see if the program could reduce depression, anxiety, PTSD, self-harm, and behavior problems in youth from Native, Hispanic, Black, and LGBTQ…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Oregon Social Learning Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC