DEPRESSION, ANXIETY

This study is testing a new mental health program for pregnant women and new mothers in Kenya. The program screens women for depression and anxiety and provides different levels of care, from counseling to specialist support, based on their needs. Researchers want to see if this …

This study aims to understand what causes severe irritability in children and teens with anxiety or depression, and to see if therapy can help. It will enroll 500 youth aged 4-17 who struggle with intense emotions and disruptive behavior. Participants will undergo detailed assess…

This program aims to reduce health inequities by connecting people in Massachusetts with support for three key health areas: cancer screening, weight management, and mental health. It will work with local clinics to offer evidence-based help to adults who are overdue for screenin…

This study is creating and testing a short questionnaire to help doctors quickly screen for anxiety and depression in children and young adults who have survived childhood cancer. The goal is to make it easier to identify those who might need more support during their regular fol…

This study is testing a new mobile phone app toolkit designed to prevent depression and anxiety in teachers and parents in Uganda. The app provides self-help resources, and participants can get support from trained community health workers. Researchers will measure if using the t…

This study is testing a new digital platform designed to help prevent suicide among teenagers in Colombia. The program includes a mobile app with self-help tools and safety planning for students, plus a training course for teachers to help them spot warning signs. Researchers wil…

This study is testing a specially adapted self-help workbook to see if it can help reduce symptoms of anxiety and depression for people living in prison. 96 participants with moderate to severe symptoms will work through the 8-week workbook program. Researchers will measure chang…

This study aims to find the best way to add support to a meditation app to help people with depression and anxiety. Researchers will test different combinations of human coaching, email support, and encouraging text messages. About 700 participants will use the app for 4 weeks an…

This study is testing whether adding an over-the-counter magnesium and vitamin B6 supplement to standard treatment helps reduce depression, anxiety, and stress in people who have recently experienced their first episode of bipolar I disorder. Researchers will compare the suppleme…

This study is testing whether psilocybin, the active compound in 'magic mushrooms,' combined with psychotherapy, can help reduce depression and anxiety in people with advanced cancer. It will involve 30 participants who are receiving ongoing cancer treatment. Researchers will mea…

This study is testing a short, single-session online course designed to help people manage symptoms of depression and anxiety. The course teaches five practical actions people can take to improve their emotional wellbeing. Researchers are enrolling 50 Canadian adults to see how h…

This early-stage study is testing whether a new AI chatbot, called Therabot-CALM, is easy to use and acceptable for people who have cannabis use disorder along with anxiety or depression. The main goal is to see if people find the app helpful and user-friendly, not to prove it tr…

This study is testing whether a smartphone app called Safe Haven can help reduce depression, anxiety, and stress in college students. Researchers will compare students using the app alongside regular campus mental health services to students receiving only standard campus care. T…

This study is exploring whether increasing access to traditional Inuit country foods and participating in cultural activities can help reduce symptoms of depression and anxiety. It involves 40 Inuit adults in Arviat, Nunavut, who will take part in community wellness programs. The…

This study is testing whether a self-guided smartphone app based on therapy principles is a practical and helpful tool for people with long-term physical conditions who are also experiencing depression or anxiety. Sixty UK residents will try the app for 12 weeks while others use …

This study is testing whether a culturally adapted skills training program called START NOW is better than usual care at reducing depression and anxiety in adolescent refugees. Researchers will enroll 80 young migrants in Switzerland and randomly assign them to either the new tra…

This study aims to train therapists to provide personalized mental health therapies to cancer patients and their caregivers who are experiencing significant distress, anxiety, depression, or sleep problems. About 100 patients and caregivers in Massachusetts will receive therapy s…

This study is testing a Spanish-language digital therapy program to help Latino adults in San Francisco manage symptoms of depression and anxiety. Researchers will enroll 213 participants to see if the program works better with peer support or on its own. The goal is to make ment…

This study aims to understand what factors make EMDR therapy more or less effective for treating depression in real-world clinical practice. Researchers will observe 40 patients receiving standard EMDR therapy from certified therapists in Italy, tracking their symptoms and the qu…

This study aims to understand how stimulating different parts of the brain with magnetic pulses affects symptoms of several mental health conditions. Researchers will enroll 180 adults with depression, anxiety, OCD, or schizophrenia to receive non-invasive brain stimulation at ra…

This study aims to understand exactly how a 7-week online mindfulness course helps people with emotional distress like depression and anxiety. Researchers will track 500 adults, comparing those taking the course to a waiting list group, to see which emotional skills improve first…

This study aims to understand if a single, brief intervention can change how people with anxiety and depression make decisions when faced with uncertainty. Researchers will measure changes in decision-making behavior and brain activity before and after the session. The goal is to…

This study aims to understand how the brain processes fear and threat in people with depression, anxiety, or both. Researchers will give 165 participants a single dose of an anxiety medication (or a placebo) and use brain scans and eye-blink tests to measure their fear responses.…