DEPRESSION

This study looked at whether adding technology to standard depression care helps cancer patients feel better. It involved 297 adults receiving cancer treatment who had significant depression. Researchers compared a tech-enhanced approach to usual care, focusing on treatment engag…

This study tested whether adding REL-1017 to standard antidepressant therapy could better reduce depression symptoms in adults with major depressive disorder. About 236 participants took either REL-1017 or a placebo pill daily, along with their usual medication. The trial was sto…

This study looked at whether a mindfulness-based program could help people who have a heart device (like an ICD or pacemaker) feel less anxious, stressed, or depressed. About 34 adults who recently got a device and had high anxiety or depression scores took part. The goal was to …

This study tested a school-based program designed to help LGBTQ high school students cope with stress, bullying, and mental health challenges like depression, anxiety, and PTSD. About 228 students from 24 high schools took part. The program aimed to reduce minority stress and imp…

This study aimed to see if a mental health app could help head and neck cancer survivors with depression. Participants would use the app for 6 weeks and fill out surveys. However, the study was stopped early and only enrolled 1 person, so no meaningful results were obtained.

This study tested a group therapy program for women suffering from long-term pelvic or belly pain. The therapy combined physical, emotional, and social support to help manage pain and improve daily life. Only 8 women took part before the study was stopped early. The main goal was…

This study tested a new drug called REL-1017 as an extra treatment for people with major depression who didn't get enough help from standard antidepressants. The trial was stopped early after enrolling 27 adults. Researchers measured changes in depression symptoms using a standar…

This study tested a program called Bounce Back, where people with mild to moderate depression get a self-help workbook and support from a trained coach over the phone. The goal was to see if this approach works better than usual care from a doctor. Only 20 people took part before…

This study looked at whether teens aged 14 to 21 with mild depression or anxiety would write articles for a website (SOVA) and if that approach was practical and acceptable. Only 12 participants were enrolled before the study was stopped. The main goal was to measure how many art…

This study tested a care coordination program for women who recently had a preterm birth. The goal was to see if the program was practical and acceptable to participants. Only 13 women enrolled before the study was stopped early.

This study followed 167 primary care patients with mental health issues like anxiety, depression, or sleep problems. Researchers used health conversations and a tool called the health curve to help improve lifestyle habits and checked a blood marker called copeptin. The goal was …

This small pilot study tested whether a decision aid could help older adults with early dementia or depression improve how they store firearms at home. Only 5 people took part, and the study was stopped early. The goal was to see if the approach was practical and acceptable, not …

This study aimed to understand how a natural brain chemical called allopregnanolone influences depression in women going through perimenopause. Researchers planned to measure changes in mood and thinking patterns. However, the study was stopped early and only enrolled 2 participa…