DELIRIUM - POSTOPERATIVE

This study tests whether finding and treating bleeding early with blood transfusions can lower the risk of delirium (sudden confusion) in people 75 and older with hip fractures. About 198 participants will be randomly assigned to either early treatment or standard care. They will…

This study compares light versus deep general anesthesia in older adults (65+ or Indigenous 55+) having major surgery. The goal is to see if lighter anesthesia reduces delirium, cognitive decline, and disability. About 2,766 participants will be randomly assigned to one of two an…

This study tests a program of sleep improvement, brain exercises, and extended pain relief for older adults having heart surgery. The goal is to reduce confusion and delirium after surgery and improve long-term recovery. About 406 people aged 60 and older will take part, with hal…

This study tests a simple "Delirium Zero" protocol to prevent delirium (sudden confusion) in older adults after hip fracture surgery. The protocol includes a clock, an orientation poster, and a checklist for family caregivers. 140 patients over 65 will be randomly assigned to eit…

This study tests whether early and intensive occupational therapy (like motivating activities and sleep routines) can reduce delirium—a state of confusion—in patients after coronary artery bypass surgery. About 300 adults in Singapore will be split into two groups: one receiving …

This pilot study tests whether playing short, personalized audio messages to elderly patients after hip fracture surgery can help prevent confusion (delirium). About 30 participants will listen to 2-minute recordings three times daily for three days. The main goal is to see if th…

This study looks at whether a drug called dexmedetomidine can help prevent confusion and memory loss in older adults after major leg surgery. Researchers will compare different doses of the drug to standard pain medicine in 75 patients. The goal is to find the best dose to protec…

This study is looking for ways to predict postoperative delirium—a state of confusion that can happen after surgery—in patients aged 65 and older. Researchers will measure certain substances in the blood before and after surgery to see if they can identify who is at risk. The goa…

This study looks at whether sleep and body-clock patterns can help predict delirium (sudden confusion) after major orthopedic surgery in adults aged 70 and older. Researchers will track sleep with a watch worn for two weeks before surgery and collect blood samples to check for Al…

This study looks at whether a special analysis of brain wave (EEG) patterns can help identify older adults who develop confusion after surgery. Researchers will compare EEG data from 90 patients aged 65 and older. The goal is to find a way to detect postoperative delirium early, …

This study looks at whether the brain's ability to use oxygen during surgery is linked to postoperative delirium (sudden confusion) in adults aged 65 and older. Researchers will measure brain oxygen levels during laparoscopic surgery using a non-invasive forehead sensor. Particip…

This study looks at how sleep problems before heart surgery might impact recovery. Researchers will collect blood and stool samples from 144 adults before and after surgery to measure changes in metabolism, inflammation, and gut bacteria. The goal is to understand why poor sleep …

This study looks at whether a simple ultrasound of the brain (transcranial Doppler) can predict confusion or memory issues after heart bypass surgery. About 106 adults having planned bypass will have their brain blood flow measured during surgery. Researchers will then check for …