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Could VR games shield aging brains from Post-Surgery confusion?

NCT ID NCT07641153

Disease control Sponsor: The Methodist Hospital Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether playing a virtual reality (VR) cognitive stimulation game can help older adults with mild memory problems stay mentally sharp and avoid delirium after major surgery. Participants, aged 65 and older, will use an Oculus Quest 2 headset for 20 minutes daily to play attention-boosting games. The study will measure how feasible, safe, and acceptable this VR approach is for this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Virtual Reality cognitive stimulation software (ReCognition) delivered via Oculus Quest 2
What this could lead to
If effective, this approach could offer a drug-free way to reduce postoperative delirium and improve recovery in older patients with cognitive decline.
What could go wrong
This is a small early-stage trial focused on feasibility, not yet on proving effectiveness. The VR intervention may not be practical or acceptable for all older patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

May 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women ≥65 years of age * Have a pre-existing diagnosis of cognitive impairment (Montreal Cognitive Assessment Score of 15-24) * Elective or emergency major surgery with the expectation of admission to the Intensive Care Unit following the surgery for three days following surgery Exclusion Criteria: * Pre-existing Intubation and invasive ventilation; * history of severe mental illness; * admission for a drug overdose; * severe vertigo; * history of severe postoperative nausea and vomiting; * hearing and visual impairment; * preexisting severe dementia (Montreal Cognitive Assessment Score \< 15; and * active delirium at the time of screening for eligibility criteria. * Active suicidal ideation or behavior Screen failure after surgery * Prolonged intubation after surgery (more than 24 hours)

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Conditions

The condition(s) this trial relates to.

delirium Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delirium Delirium, postoperative Surgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • Houston Methodist Research Insititute

    RECRUITING

    Houston, Texas, 77030, United States

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