Delirium, postoperative

This trial investigates whether a single 4 mg dose of the steroid dexamethasone, given intravenously before hip fracture surgery, can lower the risk and severity of postoperative delirium in adults aged 60 and older. Delirium is a sudden state of confusion that often occurs after…

This pilot study tests whether giving insulin as a nasal spray can prevent delirium (sudden confusion) in adults aged 65 and older after complex heart surgery. About 30 participants will receive either the insulin spray or a placebo before and after surgery. The goal is to see if…

This study looks at whether a drug called dexmedetomidine can help prevent confusion and memory loss in older adults after major leg surgery. Researchers will compare different doses of the drug to standard pain medicine in 75 patients. The goal is to find the best dose to protec…

This study tested whether playing a recording of a mother's voice to children as they wake up from anesthesia can reduce postoperative delirium. Eighty children having tonsil surgery took part. Half heard their mother's reassuring voice during recovery; the other half did not. Re…

This study analyzed health records from over 400,000 adults who had heart surgery to see if the sedative dexmedetomidine helped prevent problems like confusion, kidney injury, or death within 30 days. Researchers compared patients who received the drug around surgery time to thos…

This study looks at whether certain antibiotics given before surgery are linked to postoperative delirium in adults over 65 having elective non-cardiac surgery. Researchers will track antibiotic use and check for delirium twice daily. The goal is to provide safety evidence to gui…

This study looked at 128 children aged 2-18 who had ear, nose, or throat surgery. Researchers compared standard opioid-based anesthesia to opioid-free anesthesia to see if it reduced post-surgery agitation and delirium. The goal was to find a way to help children recover more cal…

This completed study looked at 1,000 patients who had heart surgery and were then moved to the ICU. Researchers tracked whether high or low oxygen levels increased the chance of developing delirium, a state of confusion. The goal was to understand how oxygen management might affe…

This study looked at whether a protein called S100B in the blood can help predict memory problems or confusion after surgery. Researchers followed 137 adults having elective surgery, testing their blood and thinking skills before and after the operation. The goal was to see if S1…