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Brain ultrasound may predict confusion after bypass surgery

NCT ID NCT07000461

Knowledge-focused Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing whether a simple brain ultrasound, called transcranial Doppler, can predict confusion or memory loss after heart bypass surgery. Researchers will measure blood flow in the brain during surgery and check patients for delirium and cognitive changes afterward. The goal is to see if blood flow patterns can warn doctors about who might have thinking problems after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors identify patients at risk for cognitive problems after heart surgery, allowing for earlier monitoring or preventive care.
What could go wrong
This is a small, early-stage observational study, not a treatment trial. It may not find a clear link, and results may not apply to all heart surgery patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 106 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for isolated elective cardiopulmonary bypass surgery

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-70 * Patients scheduled for isolated elective cardiopulmonary bypass surgery Exclusion Criteria: * Patients with carotid stenosis ≥50% * Emergency patients or those with a history of reoperation * Patients with a history of cerebrovascular events * Patients who do not provide consent * Patients with temporal window failure * Patients with an ejection fraction (EF) \<40% * Patients with a Mini-Mental State Examination (MMSE) score \<23 * Patients who require mechanical ventilation for more than 24 hours or those who are reintubated

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Conditions

The condition(s) this trial relates to.

coronary artery disorder delirium Emergence Delirium Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delirium, postoperative Postoperative cognitive dysfunction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bakirkoy Dr. Sadi Konuk Research and Training Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

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