DELIRIUM

This study looks at whether haloperidol, given alone or with chlorpromazine, can safely reduce severe agitation and confusion (delirium) in advanced cancer patients in a palliative care unit. About 70 participants will receive the drugs and be monitored for 24 hours. The goal is …

This study aimed to see if trazodone, a sleep aid, works better than quetiapine (an antipsychotic) or a placebo for treating delirium in adult surgical ICU patients. Delirium causes confusion, agitation, and sleep problems. The trial planned to measure how long delirium lasts, sl…

This study tests a mobile health app called iPREPARED that helps patients aged 60 and older and their caregivers prepare for a hospital stay. The app provides tips and activities to prevent or reduce delirium (sudden confusion). Researchers want to see if using the app leads to l…

This study looks at how well two drugs, haloperidol and lorazepam, can control severe agitation and confusion (delirium) in advanced cancer patients in palliative care. About 110 patients whose symptoms don't improve with low-dose haloperidol will receive different drug strategie…

This pilot study tested whether a combination of relaxation, guided imagery, and gentle massage could help prevent delirium in critically ill patients in the intensive care unit (ICU). The study involved 27 adults in the ICU who were not deeply sedated. The goal was to see if thi…

This study looks at delirium—a temporary state of confusion—in children and teens who have a stem cell transplant. Researchers will track how many children develop delirium, what raises their risk, and how it affects their hospital stay and recovery. The goal is to find ways to p…

This study looks at whether stopping overnight neurological checks in stroke patients can help prevent delirium, a state of confusion. Researchers will compare patients who get usual care with those who have overnight checks paused. The goal is to see if less sleep disruption lea…

This study planned to introduce a French version of a standard screening tool (CAPD) to detect delirium in children aged 0-18 in a pediatric intensive care unit. The goal was to measure how common delirium is in that setting. However, the study was withdrawn before enrolling any …

This study looks at why some ICU patients develop long-term thinking and memory problems. Researchers are tracking 826 adults who were in the ICU for serious conditions like respiratory failure or shock. The goal is to find risk factors, such as delirium and certain medications, …

This study looks at how memory and thinking skills change after hip or knee replacement surgery. Researchers will follow 505 adults aged 50 and older to see how many experience mental fogginess (called postoperative cognitive dysfunction) up to 4.5 months after surgery. The goal …

This study was designed to see if a noninvasive device that stimulates the vagus nerve (tcVNS) could help people wake up faster and think more clearly after anesthesia. It planned to enroll adults having lumbar spine surgery and compare the device to a sham (fake) treatment. Howe…

This study looks at 600 adults who take blood thinners and have a mild head injury but a normal first brain scan. The goal is to find out how often a delayed brain bleed or other problems like blood clots or confusion happen within 24 hours to 4 weeks after the injury. Researcher…

This study looks at how a serious injury or burn that requires ICU care can affect thinking and memory years later. Researchers are following 432 adults to measure long-term cognitive problems and understand how inflammation in the body might play a role. The goal is to learn why…

This study looks at whether a quick, automatic eye test can predict delirium (sudden confusion) in intensive care patients who need a breathing machine. Delirium is common and serious, but current detection methods are slow and require training. Researchers will measure pupil rea…