DELIRIUM

This study tests whether a portable exercise bike that attaches to hospital beds can help patients stay mobile and avoid problems like muscle loss, weakness, and confusion. About 80 adults expected to stay in the hospital for at least 3 days will use the bike for at least 15 minu…

This early-stage study tests a new injection called gastrodin in 54 healthy adults to see if it is safe and how the body processes it. The goal is to eventually use it to treat delirium, a sudden confusion often seen in hospital patients. This trial focuses only on safety and dru…

This study looks at whether adding breathing exercises and muscle relaxation to standard care can help people who have had heart surgery feel less short of breath, less anxious, and have fewer symptoms of delirium. About 116 adults will take part, with half doing the extra exerci…

This study compares two sedative drugs, remimazolam and midazolam, to see which one causes less confusion (delirium) after heart valve surgery in people aged 65 and older. Delirium is a common and serious problem after heart surgery, leading to longer hospital stays and memory is…

This study tests whether a medication called dexmedetomidine can improve sleep for patients in the intensive care unit (ICU). Poor sleep in the ICU can harm the immune system, heart, and brain. The study will compare sleep quality between two groups of 50 adults: one receiving th…

This study compares an AI-powered orientation program (AINurse) to a human nurse-led program for ICU patients. The goal is to see if the AI program can reduce delirium, anxiety, and depression, and shorten hospital stays. Ten adult ICU patients will receive either AI or nurse ori…

This study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can reduce the time older adults spend confused after heart surgery. About 144 patients aged 50 and older who develop delirium after their operation will receive eit…

This study tests whether a sleep medication called lemborexant can help older adults (65+) in the intensive care unit sleep better and reduce their risk of delirium, a common and serious confusion. One hundred patients will receive either the drug or a placebo for three nights. T…

This study aims to create a computer program that can predict delirium in ICU patients by analyzing their facial expressions and other biological features. Delirium is a sudden confusion that often goes undiagnosed. The researchers will enroll about 795 adults in the ICU and use …

This study watches brain activity in 300 adults during high-risk surgeries like heart or spine operations. Researchers use special monitors to track brain waves and pressure, linking them to patient outcomes. The goal is to understand why some people develop confusion or brain in…