CUTANEOUS MELANOMA

This is an early-stage study to find a safe dose of a new drug called KFA115, both by itself and combined with an existing immunotherapy (pembrolizumab). It involves about 126 adults with various advanced cancers that have stopped responding to standard treatments. The main goal …

This study is testing whether a new drug called acasunlimab works better alone or combined with an existing cancer drug (pembrolizumab) for people with advanced skin melanoma that has continued to grow despite prior immunotherapy. All participants will receive active treatment—no…

This early-stage study is testing the safety of a personalized vaccine made from a patient's own tumor combined with two immunotherapy drugs for advanced melanoma. The vaccine is designed to train the immune system to recognize and attack cancer cells. Researchers will enroll 11 …

This study is testing if giving an immunotherapy drug called atezolizumab before surgery is safe for people with high-risk skin melanoma that hasn't spread. The drug aims to help the patient's own immune system fight the cancer, potentially lowering the chance of it coming back a…

This study is testing an experimental virus therapy called RP1, both alone and combined with an immunotherapy drug (nivolumab), for people with advanced solid tumors that have stopped responding to standard treatments. The trial aims to find the safest and most effective dose whi…

This small, early-stage study is testing if doing 30 minutes of moderate exercise right before standard immunotherapy can help the treatment work better against certain skin cancers. Researchers will enroll 22 adults with melanoma, squamous cell carcinoma, or Merkel cell carcinom…

This study is testing if a shorter, one-year course of pembrolizumab immunotherapy works as well as the standard two-year course for people with advanced melanoma that has spread or returned. It aims to make this effective treatment more accessible and affordable within Brazil's …

This is an early-stage study to test the safety and find the right dose of a new drug called PF-08046049/SGN-BB228. It is for adults with advanced solid tumors, including melanoma, lung, colorectal, pancreatic cancer, or mesothelioma, that have stopped responding to standard trea…

This early-stage study is testing a personalized treatment called TBio-4101 for people with advanced melanoma that hasn't responded to standard therapies. Doctors take immune cells from a patient's tumor, grow them in large numbers in a lab, and then infuse them back into the pat…

This study is testing whether photos taken with smartphone apps and special imaging devices can help screen for melanoma skin cancer. Researchers are comparing these images to a standard dermatologist's exam to see if they are just as good at finding concerning moles early. About…