Tailor-Made vaccine takes on advanced melanoma in early trial
NCT ID NCT03929029
First seen Jan 06, 2026 · Last updated Jun 16, 2026 · Updated 24 times
Summary
This early-phase study tests a personalized vaccine (NeoVax) made from a patient's own tumor mutations, given alongside two immunotherapy drugs (nivolumab and ipilimumab) for advanced melanoma that cannot be surgically removed. The main goal is to check safety and find the right dose, with a secondary focus on whether the combination shrinks tumors. Only 11 participants with cutaneous melanoma are enrolled, and those with other melanoma types are excluded.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.