New drug combo targets Hard-to-Treat cancers in early trial
NCT ID NCT05544929
First seen Jan 11, 2026 · Last updated May 24, 2026 · Updated 26 times
Summary
This early-phase study tests a new drug called KFA115, alone or with pembrolizumab, in people with advanced cancers like lung, melanoma, and kidney cancer. The main goal is to find a safe dose and understand side effects. About 126 participants will take part to see if the treatment can help control the disease.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Massachusetts General Hospital .
Boston, Massachusetts, 02114, United States
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NYU School of Medicine
New York, New York, 10015, United States
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Novartis Investigative Site
Toronto, Ontario, M5G 2M9, Canada
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Novartis Investigative Site
Guangzhou, Guangdong, 510080, China
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Novartis Investigative Site
Beijing, 100036, China
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Novartis Investigative Site
Lyon, 69373, France
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Novartis Investigative Site
Dresden, Saxony, 01307, Germany
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Novartis Investigative Site
Essen, 45147, Germany
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Novartis Investigative Site
Hong Kong, 999077, Hong Kong
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Novartis Investigative Site
Milan, MI, 20133, Italy
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Novartis Investigative Site
Modena, MO, 41124, Italy
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Novartis Investigative Site
Chuo Ku, Tokyo, 104 0045, Japan
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Novartis Investigative Site
Singapore, 119074, Singapore
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Novartis Investigative Site
Seoul, 03080, South Korea
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Novartis Investigative Site
Barcelona, Catalonia, 08035, Spain
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Novartis Investigative Site
Taipei, 10002, Taiwan
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SCRI Oncology Partners
Nashville, Tennessee, 37203, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15232, United States
Conditions
Explore the condition pages connected to this study.