SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF HEAD AND NECK explained in plain language.
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New injection plus Chemo-Radiation targets tough head and neck cancers
Disease control Recruiting nowThis early-phase study is testing whether a new drug called JNJ-90301900, injected directly into tumors, is safe and works when combined with standard chemotherapy and radiation for people with advanced head and neck cancer. About 30 participants with stage III or IV cancer will …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Johnson & Johnson Enterprise Innovation Inc. • Aim: Disease control
Last updated May 26, 2026 02:33 UTC
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New drug combo trial aims to tame tough cancers
Disease control Recruiting nowThis early-stage trial tests a drug called sigvotatug vedotin, alone or with other medicines, in people with advanced solid tumors like lung, head and neck, or breast cancer. The goal is to find a safe dose and check for side effects. About 1,000 participants will join this study…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 26, 2026 02:29 UTC
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New hope for advanced cancers: experimental drug enters human trials
Disease control Recruiting nowThis study tests a new drug, BMS-986340, alone or with other cancer treatments (nivolumab or docetaxel) in people with advanced solid tumors that have worsened after standard therapy. The goal is to find safe doses and understand side effects. About 949 adults with various cancer…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated May 26, 2026 02:29 UTC
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New antibody drug takes aim at Hard-to-Treat cancers
Disease control Recruiting nowThis trial tests a new drug called UCB4594, an antibody that targets a protein (HLA-G) found on many cancer cells. The goal is to see if it helps the immune system attack tumors. It is for people with advanced solid tumors (like lung, breast, or colon cancer) that have not respon…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Cancer Research UK • Aim: Disease control
Last updated May 26, 2026 02:29 UTC
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New hope for advanced cancers: first human trial of TH9619 begins
Disease control Recruiting nowThis early-phase trial tests a new drug called TH9619 in 43 adults with advanced solid tumors (colorectal, head and neck, lung, or stomach cancer) that have not responded to prior treatment. The main goal is to find a safe dose and check for side effects. Researchers will also wa…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: One-carbon Therapeutics AB • Aim: Disease control
Last updated May 26, 2026 02:27 UTC
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New dosing strategy could improve chemo for head and neck cancer patients
Disease control Recruiting nowThis study compares two different schedules of the chemotherapy drug 5-FU in people with advanced head and neck cancer that has not responded to platinum and immunotherapy. The goal is to see which schedule works better at shrinking tumors and has fewer side effects. About 46 par…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 26, 2026 02:26 UTC
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New drug MGC026 enters human trials for advanced cancers
Disease control Recruiting nowThis study tests a new drug, MGC026, in 250 adults with advanced solid tumors that have not responded to other treatments. The goal is to check the drug's safety, find the right dose, and see if it can shrink tumors. Participants receive the drug by IV and are closely monitored f…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: MacroGenics • Aim: Disease control
Last updated May 26, 2026 02:25 UTC
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New combo aims to boost immune attack on head and neck tumors before surgery
Disease control Recruiting nowThis early-phase trial tests whether adding an experimental drug, CADI-05, to the standard immunotherapy pembrolizumab can help the immune system better attack head and neck cancer before surgery. About 22 adults with locally advanced, surgically removable cancer will receive bot…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Fox Chase Cancer Center • Aim: Disease control
Last updated May 26, 2026 02:24 UTC
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Yeast vaccine aims to stop head and neck Cancer's return
Disease control Recruiting nowThis study tests a vaccine made from candida (a type of yeast) to see if it can lower the risk of head and neck cancer returning after standard treatment. About 80 adults who have finished curative therapy and are currently cancer-free will receive either the vaccine or a placebo…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Arkansas • Aim: Disease control
Last updated May 26, 2026 02:23 UTC
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New drug duo takes on tough head and neck cancer
Disease control Recruiting nowThis study is testing a new combination of two drugs, SI-B001 and SI-B003, with or without chemotherapy, in people with advanced head and neck cancer that has spread or cannot be removed by surgery. The goal is to find the safest dose and see if the treatment can shrink tumors. A…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Sichuan Baili Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 02:23 UTC
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New hope for head and neck cancer: Triple-Drug attack tested
Disease control Recruiting nowThis study tests whether adding the drug amivantamab to standard chemotherapy and immunotherapy can help people with advanced head and neck cancer live longer. About 500 adults whose cancer has spread or returned and who have not had prior treatment for this stage will participat…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 26, 2026 02:21 UTC
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New experimental drug DM005 enters first human tests for advanced cancers
Disease control Recruiting nowThis early-stage trial tests an experimental drug, DM005, in about 136 people with advanced solid tumors like lung, head and neck, or other cancers that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see how the b…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1 • Sponsor: Doma Biopharmaceutical（Suzhou）Co., Ltd. • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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New drug cocktail aims to shrink Hard-to-Treat head and neck tumors
Disease control Recruiting nowThis study tests whether combining two drugs, sacituzumab govitecan and cetuximab, can shrink tumors in people with advanced head and neck cancer that has gotten worse after first-line therapy. About 40 adults with certain types of head and neck cancer will receive the drug combi…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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Could less chemo be better? new trial aims to reduce side effects in head and neck cancer
Disease control Recruiting nowThis study tests whether giving only 4 cycles of chemotherapy (instead of the usual 6) alongside the immunotherapy drug pembrolizumab is safe and effective for people with PD-L1-positive head and neck cancer that has come back or spread. About 86 participants will receive the sho…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Institut Claudius Regaud • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Could a drug combo supercharge immune attack on HPV head and neck cancer?
Disease control Recruiting nowThis study tests whether combining a chemotherapy drug (5-azacytidine) with an immunotherapy drug (nivolumab) can make HPV-related head and neck cancer more sensitive to the immune system. About 50 people with resectable oropharynx cancer will receive one or both drugs before the…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Barbara Burtness • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New drug combo shows promise for tough head and neck cancers
Disease control Recruiting nowThis study tests a drug called amivantamab, alone or with other treatments, in people with head and neck cancer that has come back or spread. About 287 adults will take part to see if the drug shrinks tumors and is safe. The goal is to find better ways to control the disease.
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New drug combo offers hope for tough head and neck cancers
Disease control Recruiting nowThis study is for people with head and neck cancer that has come back or spread after at least one prior treatment. It tests two antibodies (iparomlimab and tuvonralimab) given together, either alone or with chemotherapy. The goal is to see if this combination can shrink tumors o…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: The Second Affiliated Hospital of Hainan Medical University • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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New study aims to help cancer patients keep weight on during tough treatment
Symptom relief Recruiting nowThis study tests whether early, organized nutritional and supportive care can help head and neck cancer patients better tolerate combined radiation and chemotherapy after surgery. The goal is to reduce weight loss and help more patients receive the full planned treatment, which m…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Symptom relief
Last updated May 26, 2026 02:26 UTC
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New study probes hidden clues in head and neck tumors
Knowledge-focused Recruiting nowThis study aims to understand how head and neck tumors change during treatment by analyzing MRI scans and tissue samples. About 60 adults with newly diagnosed head and neck cancer who are scheduled for curative therapy will take part. Researchers will look for biological markers …
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:33 UTC
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New study aims to unlock secrets of radiation therapy in head and neck cancer
Knowledge-focused Recruiting nowThis study is for people newly diagnosed with head and neck cancer who are getting treatment with the goal of a cure. Researchers want to see how radiation therapy changes MRI scans and immune system markers in the tumor. About 40 participants will have extra MRI scans and biopsi…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 26, 2026 02:28 UTC
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Blood test may predict head and neck cancer return
Knowledge-focused Recruiting nowThis study is testing whether a blood test that looks for tumor DNA can find signs of cancer left behind after treatment for head and neck cancer. Researchers will follow 250 adults who have finished curative treatment to see if the test results match up with whether the cancer c…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 26, 2026 02:27 UTC
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Mini device implanted in tumors could personalize cancer treatment
Knowledge-focused Recruiting nowThis early-phase study tests a small implantable device that delivers tiny amounts of different drugs directly into head and neck tumors. The goal is to see which drug works best for each person before full surgery. About 30 adults with certain head and neck cancers will take par…
Matched conditions: SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC