COLON ADENOCARCINOMA
Clinical trials for COLON ADENOCARCINOMA explained in plain language.
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New hope for hard-to-treat colorectal cancer: targeted combo enters phase 3 trial
Disease control Recruiting nowThis study tests whether adding the targeted drugs MK-1084 and cetuximab to standard chemotherapy (mFOLFOX6) helps people with advanced colorectal cancer that has a KRAS G12C mutation. About 477 adults with inoperable or metastatic disease will receive either the new combination …
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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New combo aims to shrink colon tumors before surgery
Disease control Recruiting nowThis study tests whether adding a drug called tolecizumab to standard chemotherapy and immunotherapy can better shrink advanced colon cancer before surgery. About 106 adults with a specific type of colon cancer will be randomly assigned to receive the combination or standard trea…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Blood test guides next move against stubborn colon cancer
Disease control Recruiting nowThis study tests a new approach for people with colon cancer that shows signs of remaining after surgery and standard chemotherapy. Using a blood test that detects tiny bits of tumor DNA (ctDNA), doctors will switch patients to a combination of two drugs (TAS-102 and irinotecan) …
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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Could a smaller surgery spare the colon in early cancer?
Disease control Recruiting nowThis study is for people with early-stage colon cancer (stage I) who currently need a standard surgery that removes part of the colon. The new approach uses a special dye to find and remove only the tumor and the first lymph node, leaving more of the colon intact. The goal is to …
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Meander Medical Center • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC