COLON ADENOCARCINOMA
Clinical trials for COLON ADENOCARCINOMA explained in plain language.
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New drug combo shows promise in early colon cancer trial
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug dostarlimab to standard chemotherapy (CAPEOX) before surgery works better than chemotherapy alone for a common type of colon cancer (MMRp/MSS). About 120 people with stage III or T4N0 colon cancer that has not been treated ye…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 22, 2026 12:05 UTC
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New targeted combo aims to outsmart Hard-to-Treat colorectal cancer
Disease control Recruiting nowThis phase 3 trial is testing whether adding the targeted drugs calderasib and cetuximab to standard chemotherapy can help people with a specific gene mutation (KRAS G12C) in advanced colorectal cancer live longer without their cancer growing. About 477 participants will receive …
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 22, 2026 11:59 UTC
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Could a smaller surgery be just as safe for early colon cancer?
Disease control Recruiting nowThis study tests a less invasive surgery for people with early-stage colon cancer (stage I). Instead of removing a large section of the colon, doctors will remove only the tumor and a few nearby lymph nodes using a special dye. The goal is to see if this smaller surgery works as …
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Meander Medical Center • Aim: Disease control
Last updated Jun 18, 2026 11:50 UTC
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Blood test guides next move against stubborn colon cancer
Disease control Recruiting nowThis study is for people with colon cancer who still have signs of cancer in their blood (ctDNA positive) after surgery and standard chemotherapy. It tests whether switching to a combination of two drugs (trifluridine/tipiracil and irinotecan) can clear those remaining cancer cel…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Jun 18, 2026 11:48 UTC
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New combo therapy aims to boost colon cancer treatment before surgery
Disease control Recruiting nowThis study tests whether adding tolecizumab (a PCSK9 inhibitor) to standard chemoimmunotherapy can better shrink locally advanced colon cancer before surgery. About 106 adults with a specific type of colon cancer will receive either the combination or standard treatment alone. Th…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated Jun 18, 2026 11:48 UTC
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Belly fat and colon cancer: which surgery works best?
Disease control Recruiting nowThis study looks at whether keyhole surgery (laparoscopic) or traditional open surgery leads to better long-term results for colon cancer patients who have extra belly fat. About 664 adults aged 18 to 75 with colon cancer and a high Body Roundness Index will take part. The main g…
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 18, 2026 11:46 UTC
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Immunotherapy before colon surgery shows promise in early cancer trial
Disease control Recruiting nowThis study is for people with stage 1-3 colon cancer that hasn't spread. Participants receive a short course of immunotherapy (nivolumab, ipilimumab, and other drugs) for 6-12 weeks before their tumor is surgically removed. The goal is to see if this approach is safe and can shri…
Matched conditions: COLON ADENOCARCINOMA
Phase: PHASE2 • Sponsor: The Netherlands Cancer Institute • Aim: Disease control
Last updated Jun 17, 2026 12:04 UTC
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Living liver donors offer new hope for advanced colon cancer patients
Disease control Recruiting nowThis study tests whether a liver transplant from a living donor can help people with colon cancer that has spread only to the liver and cannot be removed by surgery. About 25 adults will receive a partial liver from a healthy donor. The goal is to see if this approach helps them …
Matched conditions: COLON ADENOCARCINOMA
Phase: NA • Sponsor: Azienda Ospedaliero-Universitaria di Modena • Aim: Disease control
Last updated Jun 08, 2026 13:09 UTC