COLON ADENOCARCINOMA

This study tested two different drug combinations in 240 people with advanced colorectal cancer that has a specific genetic change called HER2 amplification. One group received a combination of targeted antibodies (trastuzumab and pertuzumab), while the other received a standard …

This completed study looked at 1,471 colon cancer patients to see how their tumor's DNA repair status (pMMR vs dMMR) relates to lymph node spread and survival. Researchers hope to identify patients who might not need extensive lymph node removal. The study is observational and do…

This completed study analyzed data from 1,500 colon cancer patients to see if a new way of classifying lymph node involvement—based on both the number and location of affected nodes and tumor deposits—can better predict survival than the current standard system. Researchers colle…

This study tested whether an educational session at a church could help Latino adults learn more about colorectal cancer and feel more willing to join cancer clinical trials. Sixty Spanish-speaking participants watched videos and completed surveys. The goal was to understand barr…

This study tested whether personalized text messages could help colorectal cancer survivors eat more whole grains and less refined grains. 46 survivors who had finished active treatment received texts tailored to their needs. The main goal was to see if people would respond to th…

This study looked at how the immune system responds in people with colon cancer. Researchers collected blood and tumor tissue samples from 100 patients and followed them for up to 5 years. The goal was to understand immune cell activity, not to test a new treatment.

This study looked at over 7,000 people who had surgery for early-stage colon cancer to see how the tumor stage and lymph node involvement affect the chance of cancer returning and survival. Researchers grouped patients by tumor depth and lymph node status and tracked recurrence p…