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New combo therapy aims to boost colon cancer treatment before surgery

NCT ID NCT07468630

First seen Mar 16, 2026 · Last updated Jun 17, 2026 · Updated 12 times

Summary

This study tests whether adding tolecizumab (a PCSK9 inhibitor) to standard chemoimmunotherapy can better shrink locally advanced colon cancer before surgery. About 106 adults with a specific type of colon cancer will receive either the combination or standard treatment alone. The main goal is to see if the cancer disappears completely in the surgical sample.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Daping Hospital Third Military Medical University, chongqing, chongqing 400000 Recruiting

    RECRUITING

    Chongqing, Chongqing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colonic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.