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Blood test guides next move against stubborn colon cancer

NCT ID NCT04920032

First seen Apr 21, 2026 · Last updated Jun 17, 2026 · Updated 12 times

Summary

This study is for people with colon cancer who still have signs of cancer in their blood (ctDNA positive) after surgery and standard chemotherapy. It tests whether switching to a combination of two drugs (trifluridine/tipiracil and irinotecan) can clear those remaining cancer cells. About 22 adults with stage II–IV colon cancer will take part. The goal is to see if this approach can control the disease, not cure it, as ongoing monitoring and treatment may be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Chao Family Comprehensive Cancer Center, University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colonic neoplasm colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.