COGNITIVE CHANGE

This phase 2 study tests whether a plant-based supplement called PhytoSERM can help prevent the drop in brain activity and thinking skills that often happens during menopause. The trial includes 100 women aged 45-60 who are in early menopause and have hot flashes. Participants ta…

This study looks at whether osteopathic manipulation, a hands-on treatment for pain, can also improve thinking and memory in adults with pain. About 100 people aged 40 and older with neck, back, or shoulder pain and self-reported thinking problems will be assessed. Researchers wi…

This study compares two snacks—one with honey and nuts, the other with sugar and nuts—to see how they affect blood sugar levels after eating. Researchers want to know if honey plus nuts can lower blood sugar spikes better than sugar plus nuts, while still keeping you full and red…

This study looks at whether people with atrial fibrillation (an irregular heart rhythm) experience temporary changes in thinking, memory, or focus during an episode. About 600 participants will take tablet-based cognitive tests while in atrial fibrillation and again when their he…

This study is creating a large database of information from 250 older adults (65+) having surgery. Researchers collect blood samples, brain wave recordings, and memory tests before and after surgery. The goal is to find patterns that could one day help predict who might experienc…

This study looks at how stress impacts long-term mood and thinking skills in older adults with depression. Researchers will use brain scans to understand these changes. The goal is to find ways to prevent future problems with mood and memory.

This study looks at how memory and thinking skills change after hip or knee replacement surgery. Researchers will follow 505 adults aged 50 and older to see how many experience mental fogginess (called postoperative cognitive dysfunction) up to 4.5 months after surgery. The goal …

This study aimed to understand how changes in blood pressure when standing up affect thinking abilities and brain blood flow in people with Parkinson's disease. Researchers planned to compare those with and without orthostatic hypotension (low blood pressure upon standing) using …

This study will enroll 100,000 adults aged 45 and older to track early signs of Alzheimer's and Parkinson's disease using phone apps, voice recordings, and movement tests. Researchers aim to create better tools for early diagnosis by combining digital data with genetic and biolog…