CHRONIC LOW-BACK PAIN

This study tests three types of physical therapy for people with long-term low back pain: active exercises in water, gentle assisted movements in water, and standard exercises on land. Each treatment lasts 4 weeks with multiple supervised sessions. The goal is to see which approa…

This study tests a type of acupuncture called thread-embedding acupuncture for people with chronic low back pain. The treatment uses tiny threads placed at specific points on the back to provide longer-lasting relief. Researchers will measure changes in disability and flexibility…

This study looks at whether a program that combines structured exercises with extra daily physical activity can reduce disability and improve mental health in older adults with chronic low back pain. About 100 people aged 60 and older will be split into three groups: one doing bo…

This study tests whether combining a gentle brain stimulation technique called iTBS with yoga can help Veterans with chronic low back pain feel better and move more easily. About 213 Veterans will be assigned to receive either iTBS plus yoga or a control treatment. The goal is to…

This study looks at whether adding Pain Neuroscience Education (learning how pain works) to standard back exercises helps people with chronic low back pain feel less disabled and less afraid of movement. About 40 adults aged 25-50 will take part for 8 weeks, with follow-up at 16 …

This study looks at whether doing Pilates and resistance training can reduce pain, improve daily function, and help people with long-term low back pain sleep better. About 110 adults with chronic low back pain and poor sleep will be split into three groups: one doing both Pilates…

This study tests if a personalized digital coaching program can reduce daily activity limitations in 330 adults with chronic low back pain. Participants will either receive the coaching or continue their usual care. The main goal is to see if the digital coach helps people functi…

This study tests two natural brain molecules as safe, non-addictive pain treatments for 108 veterans with chronic low back pain. Participants will take the study drug and report pain levels over time. The goal is to find better options than opioids.

This study tests a therapy called Cognitive Functional Therapy (CFT) for people with long-term low back pain after spinal surgery. CFT combines physical exercises with mental strategies to address pain. The study will compare CFT to a sham treatment in 90 adults aged 18-75 to see…

This study tests whether adding connective tissue massage to exercise helps people with chronic low back pain more than a fake massage. Forty adults aged 18-65 with back pain for at least six months will receive either real or sham massage twice a week for eight weeks. Researcher…

This study tests a medical device called Neurolumen for people with chronic lower back pain. About 50 adults with pain lasting over 3 months will use the device to see if it reduces pain and the need for painkillers. The goal is to find a drug-free way to manage long-term back pa…

This study checks if a virtual reality (VR) version of a standard walking test (Timed Up and Go) works well for people with long-term low back pain. About 65 adults aged 18 to 55 will do the test in real life and in VR, then repeat the VR test a week later. The goal is to see if …

This study looks at how leisure activities—like hobbies, socializing, or outings—affect the quality of life of 148 adults with chronic low back pain. Participants will fill out questionnaires about their pain, daily function, and leisure engagement. The goal is to see if more act…