CHRONIC KIDNEY DISEASES

This study tests a health behavior program designed to help adults with both metabolic syndrome and chronic kidney disease reduce their waist size and improve kidney function. 160 participants will be split into two groups: one receives the program, the other standard care. Resea…

This early-phase study tests whether the drug belumosudil can help people who get a kidney transplant along with a stem cell transplant from the same donor. The goal is to see if it is safe and allows patients to stop taking most anti-rejection drugs over time. Sixteen adults wit…

This study explores whether eating more fruits and vegetables can safely manage metabolic acidosis, a common complication of chronic kidney disease. The usual treatment, sodium bicarbonate, often causes side effects and may not work well. Researchers are testing if home-delivered…

This study looks at a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to help lower blood pressure in people whose hypertension is not controlled by medication. About 1,900 adults with high blood pressure are taking part. The goal i…

This study looks at whether a natural substance called fisetin can reduce inflammation and improve stem cell function in people with advanced chronic kidney disease, including those with diabetes. About 30 adults aged 40-80 will take fisetin or a placebo for 14 days. Researchers …

This study tests a new ultrasound method that uses a contrast agent to create detailed images of blood vessels in the kidneys. Researchers want to see if this can help diagnose chronic kidney disease more accurately. The study includes both healthy volunteers and people with kidn…

This study tests a virtual health platform that provides exercise, nutrition, and psychological support to people on hemodialysis. The goal is to improve walking ability, quality of life, and overall well-being. About 70 adults with end-stage kidney disease who are stable on dial…

This study looked at over 16,600 people in Spain who had risk factors like high blood pressure or smoking, but no known heart disease. Researchers used ultrasound and urine tests to find hidden signs of artery and kidney disease. The goal is to learn what factors predict these hi…

This study is collecting information on a new dialysis machine called CARPEDIEM, designed specifically for critically ill infants with kidney problems. Researchers will track how well the machine works, how long filters last, and how many babies recover kidney function. The goal …

This study looks at muscle and fat in people with chronic kidney disease (CKD) compared to healthy volunteers. The goal is to understand how and when muscle loss happens in CKD, which could help design future treatments to improve quality of life. About 80 adults with CKD stages …

This study is testing whether adding geriatric care to regular dialysis clinics can help older adults (55+) better manage common problems like depression, memory issues, and falls. Researchers will work with patients and staff to design the new care model and then run a small tri…

This study will gather information from 5,000 adults with chronic kidney disease (CKD) to see how the disease progresses and how it is currently treated. Researchers want to find gaps between real-world care and medical guidelines, and build a model to predict which patients are …

This study aimed to see if a computer program could predict how long patients would stay in a home hospital program. Researchers used data from past patients to train the program. The study was withdrawn before enrolling any participants, so no results are available.

This study looks at how two drugs, Sacubitril/Valsartan (Entresto) and MANP, affect people with a type of heart failure where the heart pumps well but is stiff (HFpEF), along with chronic kidney disease. Researchers will measure changes in blood and urine markers after giving the…

This study tests a new educational tool to help people with chronic kidney disease (CKD) make informed decisions about pregnancy and contraception. About 70 participants will use the tool and then answer surveys to see if it helps them feel prepared. The goal is to see if this ap…

This study follows 600 people with and without chronic kidney disease (CKD) for up to 4 years to compare how often memory loss, confusion, and daily activity problems occur. Researchers will also look for risk factors that may lead to thinking problems in CKD patients. Participan…

This study is collecting health and genetic information from 120,000 people with chronic diseases like pancreatitis, inflammatory bowel disease, diabetes, and arthritis. Researchers want to understand how genes, lifestyle, and other factors affect disease progression and quality …

This study aimed to see if a computer program could predict potassium levels in the blood using a simple heart monitor. Researchers planned to use data from patients treated at home. The study was withdrawn before any participants were enrolled, so no results are available.

This study follows about 793 people with chronic kidney disease who already took part in a program to help them get kidney transplants. Researchers want to see if the program's effects last, like whether patients talk to doctors and family about transplants or find living donors.…

This study uses a special MRI technique called T1 mapping to measure changes in heart muscle tissue. Researchers will follow 8,000 adults who are already having a heart MRI to see if these measurements can help predict future health problems like heart failure or death. The goal …

This study was designed to see if using digital tools and body composition monitors could better predict how much fluid is removed during automated peritoneal dialysis. It planned to enroll adults with chronic kidney disease on dialysis for at least 3 months. However, the study w…