CHRONIC KIDNEY DISEASES

This study tests whether empagliflozin, a diabetes medicine, can reduce protein leakage in urine for people with type 2 diabetes and very advanced chronic kidney disease (eGFR between 10 and 20). About 34 adults will receive either empagliflozin or a placebo for 6 weeks each, and…

This study tests a new drug, QRX3, in 3,000 adults with chronic kidney disease (CKD) whose kidney function is declining. The goal is to see if QRX3 can slow that decline and reduce protein in the urine. Participants must have an eGFR below 60 and a slow rate of decline (less than…

This study looks at whether oral semaglutide, a drug already used for diabetes, can slow kidney disease in people who also have fatty liver disease. About 90 adults with both conditions will receive either the drug or standard care for 2 years. Researchers will track kidney funct…

This study tests whether starting four approved kidney disease medicines within 8 weeks is safe and effective for people with type 2 diabetes and chronic kidney disease. About 64 adults will be randomly assigned to either the rapid-start approach or usual care. Researchers will t…

This study checks if a new handheld device can accurately measure creatinine levels from a fingerstick blood sample at home, compared to standard lab tests. About 200 adults with kidney disease will use the device themselves and fill out a questionnaire about how easy it is to us…

This study explores whether doing virtual reality exercises during dialysis can help balance key minerals like sodium and potassium in people with end-stage kidney disease. About 40 adults aged 20-40 who have been on regular dialysis for at least 3 months will take part. The goal…

This study tests whether a program using videos and text messages can help more people with kidney failure get a transplant from a living donor. About 430 adults who are being evaluated for a kidney transplant will take part. Half will get the video-and-text program with extra su…

This observational study looks at how gum disease (periodontitis) and chronic kidney disease might be connected. Researchers will study mouth and gut bacteria in 80 adults aged 18 to 75 to see if there is a link. The goal is to better understand the relationship, not to test a tr…

This study tests whether sending reminders to doctors can increase the use of recommended medications for chronic kidney disease (CKD). About 1,000 adults with CKD will take part. The goal is to see if these alerts help more patients receive the right treatments to protect their …

This study looks at a natural chemical called kynurenine in pregnant women with and without chronic kidney disease. Researchers want to see if low levels of this chemical are linked to preeclampsia, a dangerous condition that can harm mothers and babies. About 200 women will give…

This study will use advanced MRI scans to learn more about chronic kidney disease, kidney transplants, and how kidney problems may affect the brain. Researchers will scan 180 people, including healthy volunteers and those with kidney disease, to see if MRI can help track disease …