CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

This study tracks how nerve pain from chemotherapy develops in breast cancer patients. It also tests a brain-stimulating device that may prevent this pain. 45 participants will be observed or receive the experimental treatment.

This study tests whether wearing a compression stocking on one foot during chemotherapy can prevent nerve damage (peripheral neuropathy) caused by certain cancer drugs. About 58 adults with advanced bladder or related cancers will participate, with the left foot covered and the r…

This study tests a special cooling sleeve worn on the arms and legs during chemotherapy to prevent nerve damage, a common side effect. About 80 cancer patients receiving weekly paclitaxel will try the device. Researchers will check for side effects and ask patients about numbness…

This study tests whether CBD, THC, or a mix of both can reduce nerve pain, tingling, and numbness caused by chemotherapy in breast and colon cancer survivors. About 120 people will take one of these cannabis-based compounds for 12 weeks. The goal is to see if they improve symptom…

This study tests a new way to help people with nerve damage from chemotherapy. Participants report symptoms daily via app, website, or phone for 12 weeks. One group gets standard care, while the other gets a nurse call and treatment plan if symptoms are severe. The goal is to see…

This study tests whether a small device that sends gentle electrical pulses to nerves in the leg can reduce pain from chemotherapy-induced nerve damage. Ten cancer survivors with ongoing leg pain will try the treatment and be monitored for safety and pain relief. The goal is to s…

This study tests a device called Scrambler Therapy to see if it can reduce pain, numbness, and tingling caused by chemotherapy. About 90 adults with nerve pain lasting at least three months will receive either real or sham treatment for 10 sessions. The goal is to improve daily a…

This study is looking at whether ozone therapy can improve quality of life for people with long-lasting pain, including pain caused by cancer treatments like radiation and chemotherapy. About 105 adults will receive ozone therapy as an extra treatment alongside their usual care. …

This early study is testing whether a commercially available oil made from two cannabis compounds (CBG and CBD) is safe and can help reduce nerve pain, numbness, and tingling caused by chemotherapy. About 12 adults who finished platinum-based chemo for stomach or bowel cancers wi…

This study tests whether a virtual diet program focused on lowering added sugar, increasing fiber, and eating more omega-3s can help cancer survivors manage nerve pain, numbness, and tingling caused by chemotherapy. About 50 adults who finished chemo at least three months ago and…

This study explores whether watching guided acupuncture videos can help relieve nerve pain caused by chemotherapy in breast cancer survivors. About 20 people who have finished taxane-based chemotherapy will try this approach at home. The main goal is to see if the method is pract…

This study tests if a capsaicin patch (made from chili peppers) works better than the standard drug duloxetine for nerve pain caused by chemotherapy. About 274 adults with ongoing pain in their hands and feet will be randomly assigned to one treatment for 5 weeks. The goal is to …

This study looks at whether a spinal cord stimulation device can reduce pain and improve daily life for people with nerve damage caused by chemotherapy. About 20 adults who have had chemo-related nerve pain for over six months will receive the treatment. Researchers will track pa…

This study tests whether adding compression to cold therapy (cryocompression) works as well as cold therapy alone to prevent or reduce nerve damage caused by chemotherapy in people with gynecologic cancers. About 190 participants receiving paclitaxel will be randomly assigned to …

This study tests whether a device that cools and squeezes the arms and legs during chemotherapy can prevent or lessen nerve damage (numbness, tingling, pain) caused by taxane drugs. About 50 adults with breast or gynecologic cancer will wear the device during their first round of…

This study tests whether a mobile app can teach family caregivers safe massage techniques to help cancer survivors with long-term nerve pain from chemotherapy. About 300 participants (patients and their caregivers) will use the app at home. The goal is to reduce nerve symptoms li…

This study tests whether acupuncture can ease nerve pain and numbness caused by chemotherapy in people with gynecologic, urologic, or rectal cancers. About 75 participants will be randomly assigned to receive real acupuncture, sham acupuncture, or no extra treatment. The goal is …

This study tests an experimental gel called VMD-3866 for people with nerve pain from chemotherapy (CIPN). The gel is applied to the skin and works by calming overactive nerves without entering the brain, so it's not addictive. Researchers will compare the gel to a placebo in 16 a…

This study tests whether adding ozone therapy to standard care can reduce nerve pain caused by chemotherapy. About 42 adults with cancer who have had pain for at least 3 months will receive either ozone or a placebo. The goal is to see if ozone helps with pain and quality of life…

This study tests whether combining a nerve pain drug (duloxetine) with neurofeedback—a therapy that teaches you to change your own brain waves—can better relieve chemotherapy-induced nerve damage than either treatment alone. About 380 adults with nerve pain from past chemo will b…

This study explores how certain spice compounds (cinnamaldehyde from cinnamon and capsaicin from chili peppers) affect blood flow in the fingers of people with chemotherapy-induced nerve pain. Researchers will compare 240 participants, including healthy volunteers and patients be…

This study aims to create a simple, objective tool to detect nerve damage caused by the chemotherapy drug vincristine in children and teens. By using a device that measures pupil reactions, researchers hope to catch nerve problems earlier than current methods allow. The study wil…

This study aims to find out if tiny particles in the blood, called extracellular vesicles, can predict nerve damage caused by chemotherapy. About 120 adults with certain cancers will give blood samples and answer questionnaires before, during, and after treatment. The goal is to …

This study aims to find a blood test that can identify breast cancer patients at high risk of nerve damage from the chemotherapy drug paclitaxel. Researchers will measure a protein called NFL in the blood after the first treatment cycle to see if it predicts who will need to stop…