New device could spot chemo nerve damage early in kids

NCT ID NCT04786977

Recruiting now Knowledge-focused Sponsor: Children's National Research Institute Source: ClinicalTrials.gov ↗

First seen Apr 12, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This study aims to create a simple, objective tool to detect nerve damage caused by the chemotherapy drug vincristine in children and teens. By using a device that measures pupil reactions, researchers hope to catch nerve problems earlier than current methods allow. The study will enroll 40 children aged 6-18 who are receiving vincristine as part of their leukemia treatment. The goal is to help doctors adjust chemotherapy doses to maximize cancer-killing effects while minimizing long-term nerve damage that can affect quality of life.

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Contacts and locations

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Locations

Children's National Health System
RECRUITING

Washington D.C., District of Columbia, 20010, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY