New study aims to measure Real-Life impact of chemo nerve damage
NCT ID NCT07315334
First seen Jun 24, 2026 · Last updated Aug 20, 2026 · Updated 3 times
Summary
This study will assess physical function in 80 people with chemotherapy-induced peripheral neuropathy (CIPN) using tests like balance, walking, and grip strength. Researchers will compare these objective measures with patients' own symptom reports to develop better ways to track the condition. Healthy volunteers will also be included for comparison.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better, more objective ways to measure how CIPN affects daily life, helping doctors tailor treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly improve patient outcomes, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
CIPN patients from the paracleus medical university Healthy matched controls
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Male and female patients with CIPN grade ≥ 2, according to Common Terminology Criteria for Adverse Events for peripheral sensory or motor neuropathy (CTCAE) version 5 \- Age ≥ 18 \- Ongoing or completed neuropathy-inducing chemotherapy \- Ability to stand and walk \- Ability to fill out a questionnaire Inclusion criteria for healthy controls \- Male and female adults (age ≥ 18) \- Ability to stand and walk \- Ability to fill out a questionnaire Exclusion Criteria: * Pre-existing clinically manifest peripheral neuropathy prior to start of chemotherapy (e.g. caused by radiation or malignant plexopathy, lumbar or cervical radiculopathy, carpal tunnel syndrome, B12 deficiency, AIDS, monoclonal gammopathy, diabetes, heavy metal poisoning amyloidosis, syphilis, hyperthyroidism or hypothyroidism, inherited neuropathy, etc.) Acute or chronic injuries/ diseases of the musculoskeletal system affecting functional tests \- Acute or chronic cardiovascular diseases affecting functional tests \- Neurological disease affecting functional tests (for healthy controls) \- Neurological disease other than CIPN affecting functional tests (for CIPN patients)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Institute of Physical Medicine and Rehabilitation, University Hospital Salzburg
RECRUITINGSalzburg, 5020, Austria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can ozone gas ease Chemo's lasting numbness?
- Can TENS, compression, or cold therapy stop chemo nerve pain?
- Can an antidepressant calm Chemotherapy's nerve pain?
- Retraining the senses to fight chemotherapy nerve damage
- Retraining the senses to fight chemotherapy nerve damage
- Chilling out Chemo's side effects: could cold therapy shield nerves?